Title |
Fibrolamellar Hepatocellular Carcinoma: Treatment with Yttrium-90 and Subsequent Surgical Resection
|
---|---|
Published in |
CardioVascular and Interventional Radiology, February 2018
|
DOI | 10.1007/s00270-018-1903-6 |
Pubmed ID | |
Authors |
Sebastian Mafeld, Jeremy French, Dina Tiniakos, Beate Haugk, Derek Manas, Peter Littler |
Abstract |
We describe a 52-year-old female patient who presented with a 9.5-cm fibrolamellar hepatocellular carcinoma (FL-HCC). The patient was initially unsuitable for surgical resection and therefore underwent transarterial chemoembolization followed by selective internal radiation therapy (SIRT) with Yttrium-90 to downsize the tumour. Following SIRT, the tumour decreased in volume from 350 to 20 cm3allowing curative (R0) resection with an extended left hepatectomy and reconstruction of IVC. This is the first reported case of FL-HCC treated with SIRT in which, due to the good SIRT response, the patient was downsized to allow curative resection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 38% |
Mongolia | 1 | 13% |
United Kingdom | 1 | 13% |
Canada | 1 | 13% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 4 | 50% |
Members of the public | 3 | 38% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 21% |
Researcher | 5 | 21% |
Other | 3 | 13% |
Student > Ph. D. Student | 1 | 4% |
Student > Bachelor | 1 | 4% |
Other | 1 | 4% |
Unknown | 8 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 54% |
Immunology and Microbiology | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Unknown | 7 | 29% |