| Title |
Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma: A Case Report Documenting the Potential for Very Late Tumor Recurrence
|
|---|---|
| Published in |
Head and Neck Pathology, February 2018
|
| DOI | 10.1007/s12105-018-0895-5 |
| Pubmed ID | |
| Authors |
Akeesha A. Shah, Eric D. Lamarre, Justin A. Bishop |
| Abstract |
Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma is a peculiar sinonasal tract tumor that demonstrates features of both a surface-derived and salivary gland carcinoma. Implicit in its name, this tumor has a consistent association with high-risk HPV, particularly type 33. It was first described in 2013 under the designation of HPV-related carcinoma with adenoid cystic carcinoma-like features. However, since its initial description additional cases have emerged which demonstrate a wide morphologic spectrum and relatively indolent clinical behavior. Herein we report our experience with a case of HPV-related multiphenotypic sinonasal carcinoma that was initially classified as adenoid cystic carcinoma in the 1980s. The patient recurred after a 30-year disease free interval. RNA in situ hybridization confirmed the presence of high-risk HPV in both her recurrence and her initial tumor in the 1980s, which allowed for reclassification as HPV-related multiphenotypic sinonasal carcinoma. Our case adds to the literature of this relatively newly described entity and supports the indolent clinical behavior of this neoplasm but also demonstrates a potential for very late local recurrence. |
X Demographics
The data shown below were collected from the profiles of 71 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 24 | 34% |
| Mexico | 4 | 6% |
| Spain | 3 | 4% |
| India | 2 | 3% |
| France | 2 | 3% |
| Australia | 2 | 3% |
| Turkey | 2 | 3% |
| Brazil | 2 | 3% |
| Algeria | 1 | 1% |
| Other | 7 | 10% |
| Unknown | 22 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 44 | 62% |
| Scientists | 12 | 17% |
| Practitioners (doctors, other healthcare professionals) | 11 | 15% |
| Science communicators (journalists, bloggers, editors) | 3 | 4% |
| Unknown | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 25 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 6 | 24% |
| Student > Doctoral Student | 3 | 12% |
| Researcher | 3 | 12% |
| Student > Ph. D. Student | 2 | 8% |
| Student > Postgraduate | 2 | 8% |
| Other | 2 | 8% |
| Unknown | 7 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 64% |
| Materials Science | 1 | 4% |
| Agricultural and Biological Sciences | 1 | 4% |
| Unknown | 7 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 40. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2022.
All research outputs
#1,010,181
of 25,306,238 outputs
Outputs from Head and Neck Pathology
#21
of 1,000 outputs
Outputs of similar age
#24,721
of 458,697 outputs
Outputs of similar age from Head and Neck Pathology
#2
of 21 outputs
Altmetric has tracked 25,306,238 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,000 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.