| Title |
Pharmacokinetic modeling of ethyl loflazepate (VictanR) and its main active metabolites
|
|---|---|
| Published in |
Annals of Biomedical Engineering, November 1989
|
| DOI | 10.1007/bf02367467 |
| Pubmed ID | |
| Authors |
B. B. Ba, A. Iliadis, J. P. Cano |
| Abstract |
A simultaneous consideration of plasma and urine data of unchanged drug and active metabolites, taking into account the metabolic process of the precursor, is described. The maximum likelihood principle was used to estimate parameters. This methodology is highly efficient in determining the contribution of the two main and active metabolites in the pharmacological response of ethyl loflazepate. It also may serve in the search for optimum dosage regimens in clinical practice. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 33% |
| Student > Ph. D. Student | 2 | 22% |
| Student > Bachelor | 1 | 11% |
| Student > Master | 1 | 11% |
| Unknown | 2 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 22% |
| Agricultural and Biological Sciences | 1 | 11% |
| Physics and Astronomy | 1 | 11% |
| Medicine and Dentistry | 1 | 11% |
| Chemistry | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 3 | 33% |