| Title |
Hyperserotoninemia and Altered Immunity in Autism
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, April 2006
|
| DOI | 10.1007/s10803-006-0100-7 |
| Pubmed ID | |
| Authors |
Nancy K. Burgess, Thayne L. Sweeten, William M. McMahon, Robert S. Fujinami |
| Abstract |
One of the most consistent biological findings in autism is elevated whole blood serotonin (5-HT) levels found in about 1/3 of cases. Immune abnormalities are also commonly observed in this disorder. Given 5-HT's role as an immunomodulator, possible connections between 5-HT and immune abnormalities in autism are explored in this review. Areas of focus include hyperserotoninemia and cellular immune function, autoantibodies to 5-HT receptors, and 5-HT's role in autoimmunity. Further research is needed to determine the interactions between neuropsychiatric and immune dysfunction in autism and related disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Croatia | 1 | 2% |
| Japan | 1 | 2% |
| Unknown | 62 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 14% |
| Professor > Associate Professor | 9 | 14% |
| Student > Ph. D. Student | 8 | 12% |
| Student > Master | 7 | 11% |
| Student > Postgraduate | 4 | 6% |
| Other | 13 | 20% |
| Unknown | 16 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 23% |
| Agricultural and Biological Sciences | 10 | 15% |
| Neuroscience | 8 | 12% |
| Psychology | 4 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Other | 3 | 5% |
| Unknown | 23 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2023.
All research outputs
#5,747,565
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#2,003
of 5,240 outputs
Outputs of similar age
#12,792
of 68,032 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#13
of 31 outputs
Altmetric has tracked 23,867,274 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,240 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 68,032 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.