Title |
99mTc-MAG3, a new renal imaging agent: Preliminary results in patients
|
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Published in |
European Journal of Nuclear Medicine and Molecular Imaging, October 1987
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DOI | 10.1007/bf00620476 |
Pubmed ID | |
Authors |
Andrew Taylor, Dennis Eshima, Naomi Alazraki |
Abstract |
99mTc-mercaptoacetyltriglycine (MAG3) is a new renal radiopharmaceutical which has been shown to have biological properties similar to 131I-hippurate (OIH) in animals and volunteers. 99mTc-MAG3 has now been compared with 131I-orthoiodohippurate (OIH) in a group of patients with varying degrees of renal impairment. In all cases, the 99mTc-MAG3 images were superior regardless of serum creatinine. Selected examples are illustrated including scans and renogram curves in a normal volunteer, transplant patients with creatinines of 9.8 mg/dl and 2.6 mg/dl respectively, and a furosemide study in a patient with questionable obstruction. Our preliminary results suggest that 99mTc-MAG3 performs well in patients with impaired renal function and may well provide an acceptable replacement for OIH. A kit formulation has been developed and will soon be undergoing clinical evaluation. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 1 | 33% |
Student > Master | 1 | 33% |
Unknown | 1 | 33% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 1 | 33% |
Neuroscience | 1 | 33% |
Chemistry | 1 | 33% |