| Title |
Immune-suppressive properties of the tumor microenvironment
|
|---|---|
| Published in |
Cancer Immunology, Immunotherapy, May 2013
|
| DOI | 10.1007/s00262-013-1434-6 |
| Pubmed ID | |
| Authors |
Jürgen C. Becker, Mads Hald Andersen, David Schrama, Per thor Straten |
| Abstract |
Solid tumors are more than an accumulation of cancer cells. Indeed, cancerous cells create a permissive microenvironment by exploiting non-transformed host cells. Thus, solid tumors rather resemble abnormal organs composed of the cancerous cells itself and the stroma providing the supportive framework. The stroma can be divided into the extracellular matrix consisting of proteoglycans, hyaluronic acid, and fibrous proteins, as well as stromal cells including mesenchymal and immune cells; moreover, it contains various peptide factors and metabolites. Here, we will focus on immune-modulating capacities of the tumor microenvironment. |
Mendeley readers
The data shown below were compiled from readership statistics for 233 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Japan | 1 | <1% |
| Mexico | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 229 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 47 | 20% |
| Researcher | 46 | 20% |
| Student > Bachelor | 35 | 15% |
| Student > Master | 21 | 9% |
| Student > Postgraduate | 13 | 6% |
| Other | 25 | 11% |
| Unknown | 46 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 55 | 24% |
| Biochemistry, Genetics and Molecular Biology | 38 | 16% |
| Medicine and Dentistry | 32 | 14% |
| Immunology and Microbiology | 23 | 10% |
| Chemistry | 7 | 3% |
| Other | 23 | 10% |
| Unknown | 55 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2023.
All research outputs
#4,901,379
of 23,563,389 outputs
Outputs from Cancer Immunology, Immunotherapy
#517
of 2,945 outputs
Outputs of similar age
#41,144
of 195,232 outputs
Outputs of similar age from Cancer Immunology, Immunotherapy
#14
of 27 outputs
Altmetric has tracked 23,563,389 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,945 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,232 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.