| Title |
Central nervous system toxoplasmosis in HIV pathogenesis, diagnosis, and therapy
|
|---|---|
| Published in |
Current Infectious Disease Reports, July 2000
|
| DOI | 10.1007/s11908-000-0016-x |
| Pubmed ID | |
| Authors |
Benjamin J. Luft, Arlene Chua |
| Abstract |
In patients with HIV, Toxoplasma gondii is the most frequent infectious cause of focal brain lesions. Particularly in advanced HIV disease, it can cause significant morbidity and mortality. Current clinical practice involves empiric therapy with pyrimethamine and sulfadiazine, upon a presumptive diagnosis of toxoplasmic encephalitis, based on serologic, clinical, and radiological features. This approach continues to evolve, as new diagnostic strategies, such as the use of immunoglobulin G antibody titers and polymerase chain reaction, prophylaxis against opportunistic infections, and highly active antiretroviral therapy--HAART--come into play. Primary and secondary prophylaxis are the mainstay of treatment. There remains a continuing need for development of new anti-Toxoplasma therapy. |
Mendeley readers
The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 33 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 18% |
| Researcher | 6 | 18% |
| Student > Bachelor | 5 | 15% |
| Student > Ph. D. Student | 3 | 9% |
| Other | 2 | 6% |
| Other | 4 | 12% |
| Unknown | 7 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 8 | 24% |
| Medicine and Dentistry | 7 | 21% |
| Biochemistry, Genetics and Molecular Biology | 5 | 15% |
| Veterinary Science and Veterinary Medicine | 2 | 6% |
| Nursing and Health Professions | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 7 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2021.
All research outputs
#8,513,013
of 25,382,250 outputs
Outputs from Current Infectious Disease Reports
#194
of 525 outputs
Outputs of similar age
#13,142
of 39,436 outputs
Outputs of similar age from Current Infectious Disease Reports
#2
of 8 outputs
Altmetric has tracked 25,382,250 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 525 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 39,436 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.