| Title |
Radial glia and neural stem cells
|
|---|---|
| Published in |
Cell and Tissue Research, September 2007
|
| DOI | 10.1007/s00441-007-0481-8 |
| Pubmed ID | |
| Authors |
Paolo Malatesta, Irene Appolloni, Filippo Calzolari |
| Abstract |
During the last decade, the role of radial glia has been radically revisited. Rather than being considered a mere structural component serving to guide newborn neurons towards their final destinations, radial glia is now known to be the main source of neurons in several regions of the central nervous system, notably in the cerebral cortex. Radial glial cells differentiate from neuroepithelial progenitors at the beginning of neurogenesis and share with their ancestors the bipolar shape and the expression of some molecular markers. Radial glia, however, can be distinguished from neuroepithelial progenitors by the expression of astroglial markers. Clonal analyses showed that radial glia is a heterogeneous population, comprising both pluripotent and different lineage-restricted neural progenitors. At late-embryonic and postnatal stages, radial glial cells give rise to the neural stem cells responsible for adult neurogenesis. Embryonic pluripotent radial glia and adult neural stem cells may be clonally linked, thus representing a lineage displaying stem cell features in both the developing and mature central nervous system. |
Mendeley readers
The data shown below were compiled from readership statistics for 396 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 5 | 1% |
| United Kingdom | 5 | 1% |
| France | 4 | 1% |
| United States | 3 | <1% |
| Spain | 2 | <1% |
| Russia | 2 | <1% |
| Brazil | 2 | <1% |
| Ireland | 1 | <1% |
| Chile | 1 | <1% |
| Other | 4 | 1% |
| Unknown | 367 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 110 | 28% |
| Researcher | 59 | 15% |
| Student > Master | 56 | 14% |
| Student > Bachelor | 45 | 11% |
| Student > Postgraduate | 14 | 4% |
| Other | 53 | 13% |
| Unknown | 59 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 142 | 36% |
| Neuroscience | 73 | 18% |
| Biochemistry, Genetics and Molecular Biology | 64 | 16% |
| Medicine and Dentistry | 25 | 6% |
| Engineering | 9 | 2% |
| Other | 14 | 4% |
| Unknown | 69 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2023.
All research outputs
#7,862,539
of 23,839,820 outputs
Outputs from Cell and Tissue Research
#527
of 2,279 outputs
Outputs of similar age
#25,583
of 71,250 outputs
Outputs of similar age from Cell and Tissue Research
#9
of 17 outputs
Altmetric has tracked 23,839,820 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,279 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 71,250 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.