Title |
Mind-altering with the gut: Modulation of the gut-brain axis with probiotics
|
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Published in |
Journal of Microbiology, February 2018
|
DOI | 10.1007/s12275-018-8032-4 |
Pubmed ID | |
Authors |
Namhee Kim, Misun Yun, Young Joon Oh, Hak-Jong Choi |
Abstract |
It is increasingly evident that bidirectional interactions exist among the gastrointestinal tract, the enteric nervous system, and the central nervous system. Recent preclinical and clinical trials have shown that gut microbiota plays an important role in these gut-brain interactions. Furthermore, alterations in gut microbiota composition may be associated with pathogenesis of various neurological disorders, including stress, autism, depression, Parkinson's disease, and Alzheimer's disease. Therefore, the concepts of the microbiota-gut-brain axis is emerging. Here, we review the role of gut microbiota in bidirectional interactions between the gut and the brain, including neural, immune-mediated, and metabolic mechanisms. We highlight recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders via the gut-brain axis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 4 | 13% |
United States | 3 | 9% |
Australia | 1 | 3% |
Argentina | 1 | 3% |
Brazil | 1 | 3% |
United Kingdom | 1 | 3% |
Norway | 1 | 3% |
Tunisia | 1 | 3% |
Latvia | 1 | 3% |
Other | 0 | 0% |
Unknown | 18 | 56% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 30 | 94% |
Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Scientists | 1 | 3% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 577 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 111 | 19% |
Student > Master | 80 | 14% |
Researcher | 50 | 9% |
Student > Ph. D. Student | 49 | 8% |
Student > Doctoral Student | 28 | 5% |
Other | 103 | 18% |
Unknown | 156 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 74 | 13% |
Medicine and Dentistry | 67 | 12% |
Neuroscience | 47 | 8% |
Agricultural and Biological Sciences | 46 | 8% |
Nursing and Health Professions | 36 | 6% |
Other | 128 | 22% |
Unknown | 179 | 31% |