| Title |
Redefining mouse transgenesis with CRISPR/Cas9 genome editing technology
|
|---|---|
| Published in |
Genome Biology, February 2018
|
| DOI | 10.1186/s13059-018-1409-1 |
| Pubmed ID | |
| Authors |
Gaetan Burgio |
| Abstract |
The generation of genetically modified alleles in mice using conventional transgenesis technologies is a long and inefficient process. A new study shows that the in situ delivery of CRISPR/Cas9 reagents into pregnant mice results in a high efficiency of editing, and enables the rapid generation of both simple and complex alleles. |
X Demographics
The data shown below were collected from the profiles of 40 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 18% |
| Australia | 3 | 8% |
| Japan | 3 | 8% |
| United Kingdom | 2 | 5% |
| Spain | 2 | 5% |
| Mongolia | 1 | 3% |
| Congo, The Democratic Republic of the | 1 | 3% |
| Russia | 1 | 3% |
| France | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 16 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 25 | 63% |
| Scientists | 11 | 28% |
| Practitioners (doctors, other healthcare professionals) | 2 | 5% |
| Science communicators (journalists, bloggers, editors) | 2 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 113 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 19% |
| Student > Bachelor | 15 | 13% |
| Student > Ph. D. Student | 13 | 12% |
| Student > Master | 13 | 12% |
| Student > Doctoral Student | 7 | 6% |
| Other | 17 | 15% |
| Unknown | 26 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 42 | 37% |
| Agricultural and Biological Sciences | 14 | 12% |
| Neuroscience | 7 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Medicine and Dentistry | 5 | 4% |
| Other | 10 | 9% |
| Unknown | 29 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2022.
All research outputs
#1,625,237
of 25,382,440 outputs
Outputs from Genome Biology
#1,320
of 4,468 outputs
Outputs of similar age
#35,037
of 344,055 outputs
Outputs of similar age from Genome Biology
#22
of 49 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,055 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.