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Electric Field Comparison between Microelectrode Recording and Deep Brain Stimulation Systems—A Simulation Study

Overview of attention for article published in Brain Sciences, February 2018
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Title
Electric Field Comparison between Microelectrode Recording and Deep Brain Stimulation Systems—A Simulation Study
Published in
Brain Sciences, February 2018
DOI 10.3390/brainsci8020028
Pubmed ID
Authors

Fabiola Alonso, Dorian Vogel, Johannes Johansson, Karin Wårdell, Simone Hemm

Abstract

The success of deep brain stimulation (DBS) relies primarily on the localization of the implanted electrode. Its final position can be chosen based on the results of intraoperative microelectrode recording (MER) and stimulation tests. The optimal position often differs from the final one selected for chronic stimulation with the DBS electrode. The aim of the study was to investigate, using finite element method (FEM) modeling and simulations, whether lead design, electrical setup, and operating modes induce differences in electric field (EF) distribution and in consequence, the clinical outcome. Finite element models of a MER system and a chronic DBS lead were developed. Simulations of the EF were performed for homogenous and patient-specific brain models to evaluate the influence of grounding (guide tube vs. stimulator case), parallel MER leads, and non-active DBS contacts. Results showed that the EF is deformed depending on the distance between the guide tube and stimulating contact. Several parallel MER leads and the presence of the non-active DBS contacts influence the EF distribution. The DBS EF volume can cover the intraoperatively produced EF, but can also extend to other anatomical areas. In conclusion, EF deformations between stimulation tests and DBS should be taken into consideration as they can alter the clinical outcome.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 26%
Student > Bachelor 5 13%
Researcher 5 13%
Student > Doctoral Student 2 5%
Other 2 5%
Other 4 11%
Unknown 10 26%
Readers by discipline Count As %
Engineering 8 21%
Neuroscience 7 18%
Medicine and Dentistry 6 16%
Agricultural and Biological Sciences 1 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 2 5%
Unknown 13 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2018.
All research outputs
#18,589,103
of 23,025,074 outputs
Outputs from Brain Sciences
#2,753
of 3,925 outputs
Outputs of similar age
#327,809
of 437,336 outputs
Outputs of similar age from Brain Sciences
#36
of 48 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,925 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 437,336 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.