Title |
An Update on Systemic Sclerosis-Associated Pulmonary Arterial Hypertension: a Review of the Current Literature
|
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Published in |
Current Rheumatology Reports, February 2018
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DOI | 10.1007/s11926-018-0709-5 |
Pubmed ID | |
Authors |
Sneha M. Sundaram, Lorinda Chung |
Abstract |
This review will summarize the most current literature on the clinical impact, epidemiology, risk factors, screening recommendations, predictors of outcomes, and treatment options in patients with pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc). PAH continues to be a major cause of morbidity and mortality in SSc. Many risk factors and predictors of outcomes have been identified in patients with SSc including clinical, hemodynamic, and laboratory parameters. Screening for PAH in SSc patients is important and screening algorithms have been developed. Despite many available treatment options for PAH, prognosis remains poor. Awareness of risk factors, early detection, and up-front combination treatment are important considerations in SSc-PAH and may lead to improved outcomes. Further research to develop better biomarkers and therapies is needed to continue to improve survival and outcomes in patients with SSc-PAH. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 67 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 10 | 15% |
Researcher | 8 | 12% |
Student > Master | 7 | 10% |
Other | 6 | 9% |
Student > Ph. D. Student | 4 | 6% |
Other | 11 | 16% |
Unknown | 21 | 31% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 30 | 45% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Immunology and Microbiology | 4 | 6% |
Agricultural and Biological Sciences | 2 | 3% |
Nursing and Health Professions | 1 | 1% |
Other | 1 | 1% |
Unknown | 25 | 37% |