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X Demographics
Mendeley readers
Attention Score in Context
| Title |
FoxP3 isoforms and PD-1 expression by T regulatory cells in multiple sclerosis
|
|---|---|
| Published in |
Scientific Reports, February 2018
|
| DOI | 10.1038/s41598-018-21861-5 |
| Pubmed ID | |
| Authors |
Manolo Sambucci, Francesca Gargano, Veronica De Rosa, Marco De Bardi, Mario Picozza, Roberta Placido, Serena Ruggieri, Alessia Capone, Claudio Gasperini, Giuseppe Matarese, Luca Battistini, Giovanna Borsellino |
| Abstract |
Forkhead box P3 (FoxP3)+ regulatory T cells (Treg) are powerful mediators of immune regulation and immune homeostasis. In humans, Tregs are a heterogeneous population expressing surface markers which define phenotypically and functionally distinct subsets. Moreover, it is now clear that intracellular staining for FoxP3 does not unequivocally identify "true" suppressor cells, since several FoxP3 isoforms exist, and different reagents for FoxP3 detection are available. Here, we propose a strategy to identify potentially functional and suppressive Treg cells in an autoimmune disease like multiple sclerosis, and we suggest that in patients affected by this disease these cells are both reduced in number and functionally exhausted. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 13% |
| Russia | 1 | 13% |
| France | 1 | 13% |
| Unknown | 5 | 63% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 88% |
| Science communicators (journalists, bloggers, editors) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 100 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 14% |
| Student > Ph. D. Student | 12 | 12% |
| Researcher | 10 | 10% |
| Other | 10 | 10% |
| Student > Bachelor | 9 | 9% |
| Other | 14 | 14% |
| Unknown | 31 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 19 | 19% |
| Biochemistry, Genetics and Molecular Biology | 16 | 16% |
| Medicine and Dentistry | 14 | 14% |
| Agricultural and Biological Sciences | 7 | 7% |
| Neuroscience | 7 | 7% |
| Other | 2 | 2% |
| Unknown | 35 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2018.
All research outputs
#1,599,965
of 23,025,074 outputs
Outputs from Scientific Reports
#15,003
of 124,372 outputs
Outputs of similar age
#37,446
of 330,058 outputs
Outputs of similar age from Scientific Reports
#530
of 3,986 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 124,372 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,058 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 3,986 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.