Title |
Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications
|
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Published in |
ACS Applied Materials & Interfaces, February 2018
|
DOI | 10.1021/acsami.7b18596 |
Pubmed ID | |
Authors |
Aaqil Rifai, Nhiem Tran, Desmond W. Lau, Aaron Elbourne, Hualin Zhan, Alastair D. Stacey, Edwin L. H. Mayes, Avik Sarker, Elena P. Ivanova, Russell J. Crawford, Phong A. Tran, Brant C. Gibson, Andrew D. Greentree, Elena Pirogova, Kate Fox |
Abstract |
Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create of bespoke items across many diverse fields such as medicine, defence and aerospace. Despite great progress in orthopaedic implant applications, such as for 'just in time' implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general, and especially show promise for improved biomedical implants. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 7 | 70% |
United States | 2 | 20% |
Unknown | 1 | 10% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 50% |
Scientists | 5 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 80 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 12 | 15% |
Researcher | 10 | 13% |
Student > Master | 10 | 13% |
Student > Doctoral Student | 7 | 9% |
Student > Bachelor | 4 | 5% |
Other | 8 | 10% |
Unknown | 29 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 17 | 21% |
Materials Science | 10 | 13% |
Chemistry | 7 | 9% |
Physics and Astronomy | 4 | 5% |
Immunology and Microbiology | 2 | 3% |
Other | 7 | 9% |
Unknown | 33 | 41% |