Title |
Ljungan virus is endemic in rodents in the UK
|
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Published in |
Archives of Virology, May 2013
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DOI | 10.1007/s00705-013-1731-6 |
Pubmed ID | |
Authors |
Anne-Marie Salisbury, Michael Begon, Winifred Dove, Bo Niklasson, James P. Stewart |
Abstract |
Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. LjV has been associated with [corrected] type 1 diabetes-like symptoms and myocarditis in bank voles (Myodes glareolus), and it has been suggested that it has zoonotic potential. Here, we show for the first time that Ljungan virus is prevalent (20-27 % positive by PCR) in four species of UK rodent (Myodes glareolus [bank vole], Apodemus sylvaticus [wood mouse], Microtus agrestis [field vole] and Mus musculus [house mouse]). Sequence analysis showed that Ljungan virus of genotypes 1 and 2 were present, although genotype 1 was more prevalent and more frequently associated with brain tissue. This study highlights the prevalence of Ljungan virus in the UK and the need for assessment [corrected] of its zoonotic potential. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
China | 1 | 3% |
Unknown | 30 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 28% |
Researcher | 6 | 19% |
Student > Master | 5 | 16% |
Student > Bachelor | 3 | 9% |
Student > Postgraduate | 2 | 6% |
Other | 2 | 6% |
Unknown | 5 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 41% |
Biochemistry, Genetics and Molecular Biology | 6 | 19% |
Medicine and Dentistry | 4 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Unspecified | 1 | 3% |
Other | 2 | 6% |
Unknown | 5 | 16% |