Title |
Genetic architecture of obesity and related metabolic traits—recent insights from isolated populations
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Published in |
Current Opinion in Genetics & Development, March 2018
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DOI | 10.1016/j.gde.2018.02.010 |
Pubmed ID | |
Authors |
Mette Korre Andersen, Niels Grarup, Ida Moltke, Anders Albrechtsen, Torben Hansen |
Abstract |
In this mini-review, we give an overview of what is known about the genetic architecture of obesity and related metabolic traits with a primary focus on recent insights from studies of historically small and isolated populations. We start by briefly explaining what genetic architecture is and why studies of isolated populations in general are valuable if we want a complete picture of the genetic architecture of diseases and other traits among humans. Then we contrast what is known about the genetic architecture of obesity and related metabolic traits among large outbred populations, like Europeans, with results from recent studies of isolated populations. Finally, we briefly discuss the perspectives of studying isolated populations to gain insight into genetic architecture in humans. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 21% |
Student > Master | 6 | 21% |
Student > Bachelor | 3 | 11% |
Researcher | 3 | 11% |
Student > Doctoral Student | 1 | 4% |
Other | 4 | 14% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 9 | 32% |
Agricultural and Biological Sciences | 5 | 18% |
Medicine and Dentistry | 5 | 18% |
Computer Science | 2 | 7% |
Neuroscience | 2 | 7% |
Other | 0 | 0% |
Unknown | 5 | 18% |