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Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation

Overview of attention for article published in Nucleic Acids Research, March 2007
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

patent
1 patent
wikipedia
3 Wikipedia pages

Citations

dimensions_citation
111 Dimensions

Readers on

mendeley
130 Mendeley
citeulike
1 CiteULike
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Title
Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation
Published in
Nucleic Acids Research, March 2007
DOI 10.1093/nar/gkm035
Pubmed ID
Authors

Ivaylo P. Ivanov, John F. Atkins

Abstract

The protein antizyme is a negative regulator of intracellular polyamine levels. Ribosomes synthesizing antizyme start in one ORF and at the codon 5' adjacent to its stop codon, shift +1 to a second and partially overlapping ORF which encodes most of the protein. The ribosomal frameshifting is a sensor and effector of an autoregulatory circuit which is conserved in animals, fungi and protists. Stimulatory signals encoded 5' and 3' of the shift site act to program the frameshifting. Despite overall conservation, many individual branches have evolved specific features surrounding the frameshift site. Among these are RNA pseudoknots, RNA stem-loops, conserved primary RNA sequences, nascent peptide sequences and branch-specific 'shifty' codons.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 3%
Austria 1 <1%
Germany 1 <1%
Japan 1 <1%
India 1 <1%
Unknown 122 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 18%
Student > Ph. D. Student 22 17%
Student > Bachelor 15 12%
Student > Master 13 10%
Student > Doctoral Student 11 8%
Other 19 15%
Unknown 27 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 57 44%
Biochemistry, Genetics and Molecular Biology 33 25%
Medicine and Dentistry 4 3%
Computer Science 1 <1%
Immunology and Microbiology 1 <1%
Other 5 4%
Unknown 29 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 March 2021.
All research outputs
#4,696,232
of 22,786,691 outputs
Outputs from Nucleic Acids Research
#7,257
of 26,310 outputs
Outputs of similar age
#14,629
of 76,381 outputs
Outputs of similar age from Nucleic Acids Research
#22
of 103 outputs
Altmetric has tracked 22,786,691 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26,310 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 76,381 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.