Title |
Evolutionary analysis of Porcine circovirus 3 (PCV3) indicates an ancient origin for its current strains and a worldwide dispersion
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Published in |
Virus Genes, March 2018
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DOI | 10.1007/s11262-018-1545-4 |
Pubmed ID | |
Authors |
Giuliana Loreto Saraiva, Pedro Marcus Pereira Vidigal, Juliana Lopes Rangel Fietto, Gustavo Costa Bressan, Abelardo Silva Júnior, Márcia Rogéria de Almeida |
Abstract |
Porcine circovirus 3 (PCV3) is an emerging virus that was identified in the United States in 2016. Since its first identification, PCV3 has been identified in Brazil, China, United States, Poland, and Republic of Korea. In this study, we used molecular phylogenetic analysis of available sequences to address questions surrounding the emergence of PCV3 in porcine world industry. Our data indicate that PCV3 did not emerge through recombination events among currently known circoviruses and that its speciation is not a recent evolutionary event. The most common recent ancestor analysis suggests that PCV3 lineages have emerged over the past 50 years. PCV3 is not genetically closely related with other Porcine circovirus and it has been evolving undetected for some time in swine and probably in bovine population. We also found groups of genetically related isolates of PCV3 originated from different countries that may be associated with dispersal routes, suggesting that PCV3 has already been circulating in pig-producing countries for some time before its first detection. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 53 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 23% |
Student > Doctoral Student | 7 | 13% |
Professor | 4 | 8% |
Student > Bachelor | 4 | 8% |
Student > Master | 4 | 8% |
Other | 10 | 19% |
Unknown | 12 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 23 | 43% |
Biochemistry, Genetics and Molecular Biology | 7 | 13% |
Agricultural and Biological Sciences | 5 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Unspecified | 1 | 2% |
Other | 2 | 4% |
Unknown | 14 | 26% |