Title |
A Randomized Trial of Yogurt for Prevention of Antibiotic-Associated Diarrhea
|
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Published in |
Digestive Diseases and Sciences, October 2003
|
DOI | 10.1023/a:1026155328638 |
Pubmed ID | |
Authors |
Ripudaman S. Beniwal, Vincent C. Arena, Leno Thomas, Sudhir Narla, Thomas F. Imperiale, Rauf A. Chaudhry, Usman A. Ahmad |
Abstract |
Antibiotic-associated diarrhea (AAD) is the most common adverse effect of antibiotic therapy. Our aim was to determine the effectiveness of a dietary supplement of yogurt for prevention of AAD. Two hundred two hospitalized patients receiving oral or intravenous antibiotics were randomized to receive or not receive a dietary yogurt supplement, consisting of 227 grams of commercial yogurt, and followed for 8 days. Mean age of the study group was 70 years and 43% were male. Compliance and 8-day follow-up were 85% and 91%, respectively. Patients receiving yogurt reported less frequent diarrhea (12% vs 24%; P = 0.04), and significantly less total diarrhea] days (23 vs 60). The cumulative proportions of patients without diarrhea were significantly different (P = 0.02) between patients receiving and not receiving yogurt. For conclusion, dietary supplementation with yogurt is a simple, effective, and safe treatment that decreases the incidence and duration of AAD. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Norway | 1 | 1% |
Unknown | 74 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 10 | 13% |
Student > Ph. D. Student | 10 | 13% |
Student > Bachelor | 8 | 11% |
Student > Master | 7 | 9% |
Researcher | 6 | 8% |
Other | 17 | 23% |
Unknown | 17 | 23% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 17 | 23% |
Medicine and Dentistry | 14 | 19% |
Nursing and Health Professions | 6 | 8% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Immunology and Microbiology | 3 | 4% |
Other | 8 | 11% |
Unknown | 23 | 31% |