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ERAD: the long road to destruction

Overview of attention for article published in Nature Cell Biology, August 2005
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (65th percentile)

Mentioned by

patent
8 patents
wikipedia
2 Wikipedia pages

Citations

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1022 Dimensions

Readers on

mendeley
869 Mendeley
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3 CiteULike
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1 Connotea
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Title
ERAD: the long road to destruction
Published in
Nature Cell Biology, August 2005
DOI 10.1038/ncb0805-766
Pubmed ID
Authors

Birgit Meusser, Christian Hirsch, Ernst Jarosch, Thomas Sommer

Abstract

Endoplasmic reticulum (ER)-associated protein degradation (ERAD) eliminates misfolded or unassembled proteins from the ER. ERAD targets are selected by a quality control system within the ER lumen and are ultimately destroyed by the cytoplasmic ubiquitin-proteasome system (UPS). The spatial separation between substrate selection and degradation in ERAD requires substrate transport from the ER to the cytoplasm by a process termed dislocation. In this review, we will summarize advances in various aspects of ERAD and discuss new findings on how substrate dislocation is achieved.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 869 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 9 1%
Germany 6 <1%
Spain 2 <1%
United Kingdom 2 <1%
Brazil 2 <1%
Mexico 2 <1%
France 1 <1%
South Africa 1 <1%
Israel 1 <1%
Other 9 1%
Unknown 834 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 234 27%
Student > Bachelor 118 14%
Researcher 116 13%
Student > Master 109 13%
Professor 35 4%
Other 122 14%
Unknown 135 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 346 40%
Biochemistry, Genetics and Molecular Biology 215 25%
Medicine and Dentistry 56 6%
Immunology and Microbiology 22 3%
Chemistry 22 3%
Other 65 7%
Unknown 143 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2020.
All research outputs
#5,611,796
of 26,017,215 outputs
Outputs from Nature Cell Biology
#2,221
of 4,184 outputs
Outputs of similar age
#13,395
of 71,003 outputs
Outputs of similar age from Nature Cell Biology
#9
of 29 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,184 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.7. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 71,003 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.