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Interleukin 18 and Periodontal Disease

Overview of attention for article published in Critical Reviews in Oral Biology & Medicine, November 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

patent
1 patent
wikipedia
3 Wikipedia pages

Citations

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46 Dimensions

Readers on

mendeley
22 Mendeley
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Title
Interleukin 18 and Periodontal Disease
Published in
Critical Reviews in Oral Biology & Medicine, November 2016
DOI 10.1177/154405910708600702
Pubmed ID
Authors

A. Orozco, E. Gemmell, M. Bickel, G.J. Seymour

Abstract

Cytokines are of major importance in periodontal disease progression. It is generally agreed that control of the Th1/Th2 balance is central to the immunoregulation of periodontal disease. There is increasing evidence in humans that the stable periodontal lesion is mediated by Th1 cells, while the progressive lesion sees a shift toward Th2 cells. Equally, there is conflicting evidence, mainly in animal models, that bone loss is mediated by Th1 responses, and that Th2 responses are protective. In the presence of IL-12, IL-18 induces Th1 responses while, in the absence of IL-12, it promotes Th2 responses. It is clear, therefore, that since IL-18 has the ability to induce either Th1 or Th2 differentiation, it becomes important to consider its role in periodontal disease. This review endeavors to give an overview of this cytokine and its relevance for periodontal disease.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 4 18%
Student > Ph. D. Student 4 18%
Student > Doctoral Student 3 14%
Student > Bachelor 1 5%
Other 1 5%
Other 3 14%
Unknown 6 27%
Readers by discipline Count As %
Medicine and Dentistry 9 41%
Agricultural and Biological Sciences 3 14%
Environmental Science 1 5%
Biochemistry, Genetics and Molecular Biology 1 5%
Immunology and Microbiology 1 5%
Other 1 5%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2021.
All research outputs
#5,448,088
of 25,377,790 outputs
Outputs from Critical Reviews in Oral Biology & Medicine
#821
of 3,870 outputs
Outputs of similar age
#97,008
of 415,112 outputs
Outputs of similar age from Critical Reviews in Oral Biology & Medicine
#273
of 1,860 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,870 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 415,112 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 1,860 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.