| Title |
Isolation and identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet
|
|---|---|
| Published in |
Parasitology Research, January 2008
|
| DOI | 10.1007/s00436-007-0864-5 |
| Pubmed ID | |
| Authors |
A. Abdul Rahuman, Geetha Gopalakrishnan, P. Venkatesan, Kannappan Geetha |
| Abstract |
Larvicidal activity of crude hexane, ethyl acetate, petroleum ether, acetone and methanol extracts of five medicinal plants, Abutilon indicum, Aegle marmelos, Euphorbia thymifolia, Jatropha gossypifolia and Solanum torvum were assayed for their toxicity against the early fourth-instar larvae of Culex quinquefasciatus. The larval mortality was observed after 24 h exposure. All extracts showed moderate larvicidal effects; however, the highest larval mortality was found in petroleum ether extract of A. indicum. In the present study, bioassay-guided fractionation of A. indicum led to the separation and identification of a beta-sitosterol as a potential new mosquito larvicidal compound with LC50 value of 11.49, 3.58 and 26.67 ppm against Aedes aegypti L, Anopheles stephensi Liston and C. quinquefasciatus Say (Diptera: Culicidae), respectively. 1H NMR, 13C NMR and mass spectral data confirmed the identification of the active compound. beta-sitosterol has been recognized as the active ingredient of many medicinal plant extracts. All the crude extracts when screened for their larvicidal activities indicated toxicity against the larvae of C. quinquefasciatus. This article reports the isolation and identification of the beta-sitosterol as well as bioassay data for the crude extracts. There are no reports of beta-sitosterol in the genus A. indicum, and their larvicidal activities are being evaluated for the first time. Results of this study show that the petroleum ether extract of A. indicum may be considered as a potent source and beta-sitosterol as a new natural mosquito larvicidal agent. |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 103 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 18% |
| Student > Ph. D. Student | 14 | 13% |
| Researcher | 7 | 7% |
| Student > Bachelor | 7 | 7% |
| Other | 6 | 6% |
| Other | 15 | 14% |
| Unknown | 37 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 32% |
| Chemistry | 9 | 9% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
| Medicine and Dentistry | 3 | 3% |
| Other | 8 | 8% |
| Unknown | 41 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2013.
All research outputs
#7,453,479
of 22,786,691 outputs
Outputs from Parasitology Research
#621
of 3,782 outputs
Outputs of similar age
#41,761
of 156,228 outputs
Outputs of similar age from Parasitology Research
#3
of 29 outputs
Altmetric has tracked 22,786,691 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,782 research outputs from this source. They receive a mean Attention Score of 2.7. This one has gotten more attention than average, scoring higher than 66% of its peers.
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We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.