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Technology Insight: applications of emerging immunotherapeutic strategies for Epstein–Barr virus-associated malignancies

Overview of attention for article published in Nature Reviews Clinical Oncology, March 2005
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Title
Technology Insight: applications of emerging immunotherapeutic strategies for Epstein–Barr virus-associated malignancies
Published in
Nature Reviews Clinical Oncology, March 2005
DOI 10.1038/ncponc0107
Pubmed ID
Authors

Rajiv Khanna, Denis Moss, Maher Gandhi

Abstract

The Epstein-Barr virus (EBV) is uniquely associated with a broad range of human malignancies. In spite of their diverse cellular origin, most of these malignancies share common features, including the expression of either some or all of the EBV latent proteins, which can be potentially exploited for immune-based therapies. Here we discuss new and emerging strategies to manipulate the immune response to specifically boost T-cell immunity towards viral proteins that are expressed in EBV-associated malignancies. These strategies are used either alone or as an adjuvant therapy in combination with chemotherapy and/or monoclonal antibodies. Overall, this strategy may serve as a new paradigm for the successful multi-modality treatment of malignancies.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 7%
Sweden 1 7%
Unknown 13 87%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 40%
Researcher 2 13%
Other 2 13%
Student > Master 2 13%
Unknown 3 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 33%
Biochemistry, Genetics and Molecular Biology 4 27%
Arts and Humanities 1 7%
Immunology and Microbiology 1 7%
Medicine and Dentistry 1 7%
Other 0 0%
Unknown 3 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 July 2019.
All research outputs
#8,534,976
of 25,373,627 outputs
Outputs from Nature Reviews Clinical Oncology
#1,387
of 2,340 outputs
Outputs of similar age
#26,427
of 76,621 outputs
Outputs of similar age from Nature Reviews Clinical Oncology
#5
of 10 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,340 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.8. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 76,621 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.