| Title |
Biosynthesis of isoprenoids via the non-mevalonate pathway
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, June 2004
|
| DOI | 10.1007/s00018-004-3381-z |
| Pubmed ID | |
| Authors |
W. Eisenreich, A. Bacher, D. Arigoni, F. Rohdich |
| Abstract |
The mevalonate pathway for the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), is known in considerable detail. Only recently, the existence of a second mevalonate-independent pathway for the biosynthesis of IPP and DMAPP was detected in plants and certain eubacteria. Experiments with 13C and/or 2H-labelled precursors were crucial in the elucidation of this novel route. The pathway is essential in plants, many eubacteria and apicomplexan parasites, but not in archaea and animals. The genes, enzymes and intermediates of this pathway were rapidly unravelled over the past few years. Detailed knowledge about the mechanisms of this novel route may benefit the development of novel antibiotics, antimalarials and herbicides. |
Mendeley readers
The data shown below were compiled from readership statistics for 588 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 1% |
| Germany | 3 | <1% |
| Chile | 3 | <1% |
| Japan | 3 | <1% |
| United Kingdom | 3 | <1% |
| Mexico | 3 | <1% |
| Austria | 1 | <1% |
| Sweden | 1 | <1% |
| France | 1 | <1% |
| Other | 7 | 1% |
| Unknown | 556 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 139 | 24% |
| Student > Master | 89 | 15% |
| Researcher | 70 | 12% |
| Student > Bachelor | 64 | 11% |
| Student > Doctoral Student | 41 | 7% |
| Other | 76 | 13% |
| Unknown | 109 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 204 | 35% |
| Biochemistry, Genetics and Molecular Biology | 104 | 18% |
| Chemistry | 94 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 2% |
| Engineering | 11 | 2% |
| Other | 45 | 8% |
| Unknown | 117 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2020.
All research outputs
#3,108,935
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#465
of 4,151 outputs
Outputs of similar age
#5,026
of 58,626 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#1
of 14 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,626 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.