Title |
Prompt control of bronchorrhea in patients with bronchioloalveolar carcinoma treated with gefitinib (Iressa)
|
---|---|
Published in |
Supportive Care in Cancer, November 2004
|
DOI | 10.1007/s00520-004-0717-z |
Pubmed ID | |
Authors |
Daniel T. Milton, Mark G. Kris, Jorge E. Gomez, Marc B. Feinstein |
Abstract |
Bronchorrhea is a condition in which voluminous sputum is produced daily, typically seen with bronchioloalveolar cell carcinoma (BAC). Unless the underlying cancer can be controlled, bronchorrhea causes substantial symptomatic distress. We report two cases of bronchorrhea associated with advanced BAC successfully treated with the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, gefitinib. Prompt resolution of these patients' bronchorrhea, dyspnea, and supplemental oxygen requirements are detailed. Given the limited success of alternative interventions, a trial of gefitinib should be considered for patients with bronchorrhea secondary to BAC. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 2 | 17% |
Professor > Associate Professor | 2 | 17% |
Student > Ph. D. Student | 1 | 8% |
Lecturer > Senior Lecturer | 1 | 8% |
Other | 1 | 8% |
Other | 1 | 8% |
Unknown | 4 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 50% |
Agricultural and Biological Sciences | 1 | 8% |
Nursing and Health Professions | 1 | 8% |
Unknown | 4 | 33% |