↓ Skip to main content

Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

Overview of attention for article published in Science, December 2003
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

twitter
1 X user
patent
33 patents
wikipedia
18 Wikipedia pages

Citations

dimensions_citation
1210 Dimensions

Readers on

mendeley
593 Mendeley
citeulike
14 CiteULike
connotea
6 Connotea
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays
Published in
Science, December 2003
DOI 10.1126/science.1090100
Pubmed ID
Authors

Jason M. Johnson, John Castle, Philip Garrett-Engele, Zhengyan Kan, Patrick M. Loerch, Christopher D. Armour, Ralph Santos, Eric E. Schadt, Roland Stoughton, Daniel D. Shoemaker

Abstract

Alternative pre-messenger RNA (pre-mRNA) splicing plays important roles in development, physiology, and disease, and more than half of human genes are alternatively spliced. To understand the biological roles and regulation of alternative splicing across different tissues and stages of development, systematic methods are needed. Here, we demonstrate the use of microarrays to monitor splicing at every exon-exon junction in more than 10,000 multi-exon human genes in 52 tissues and cell lines. These genome-wide data provide experimental evidence and tissue distributions for thousands of known and novel alternative splicing events. Adding to previous studies, the results indicate that at least 74% of human multi-exon genes are alternatively spliced.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 593 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 14 2%
Germany 7 1%
United Kingdom 6 1%
France 3 <1%
Italy 3 <1%
China 3 <1%
Poland 2 <1%
Spain 2 <1%
Australia 1 <1%
Other 8 1%
Unknown 544 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 163 27%
Researcher 139 23%
Professor > Associate Professor 55 9%
Student > Master 41 7%
Student > Bachelor 38 6%
Other 96 16%
Unknown 61 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 281 47%
Biochemistry, Genetics and Molecular Biology 119 20%
Medicine and Dentistry 38 6%
Computer Science 16 3%
Neuroscience 16 3%
Other 47 8%
Unknown 76 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2023.
All research outputs
#2,517,047
of 23,839,820 outputs
Outputs from Science
#30,012
of 78,844 outputs
Outputs of similar age
#6,134
of 136,255 outputs
Outputs of similar age from Science
#75
of 261 outputs
Altmetric has tracked 23,839,820 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 78,844 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 63.8. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 136,255 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 261 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.