| Title |
Regulation of Cortical Neuron Migration by the Reelin Signaling Pathway
|
|---|---|
| Published in |
Neurochemical Research, January 2011
|
| DOI | 10.1007/s11064-011-0407-4 |
| Pubmed ID | |
| Authors |
Takao Honda, Kazuma Kobayashi, Katsuhiko Mikoshiba, Kazunori Nakajima |
| Abstract |
Reeler is a mutant mouse with defects in layered structures of the central nervous system, such as the cerebral cortex, hippocampus, and cerebellum, and has been extensively examined for more than half a century. The full-length cDNA for the responsible gene for reeler, reelin, was serendipitously identified, revealing that Reelin encodes a large secreted protein. So far, two Reelin receptors, apolipoprotein E receptor 2 and very low-density lipoprotein receptor, and the cytoplasmic adaptor protein Disabled homolog 1 (Dab1) have been shown to be essential for Reelin signaling. Although a number of downstream cascades of Dab1 have also been reported using various experimental systems, the physiological functions of Reelin in vivo remain controversial. Here, we review recent advances in the understanding of the Reelin-Dab1 signaling pathway in the developing cerebral cortex. |
Mendeley readers
The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 3% |
| Turkey | 1 | <1% |
| Belgium | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 97 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 29 | 28% |
| Researcher | 19 | 18% |
| Student > Ph. D. Student | 18 | 17% |
| Student > Postgraduate | 9 | 9% |
| Student > Bachelor | 8 | 8% |
| Other | 16 | 15% |
| Unknown | 5 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 50 | 48% |
| Neuroscience | 25 | 24% |
| Medicine and Dentistry | 14 | 13% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Psychology | 1 | <1% |
| Other | 2 | 2% |
| Unknown | 5 | 5% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2016.
All research outputs
#7,453,827
of 22,787,797 outputs
Outputs from Neurochemical Research
#589
of 2,095 outputs
Outputs of similar age
#55,421
of 182,537 outputs
Outputs of similar age from Neurochemical Research
#9
of 19 outputs
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