| Title |
An Investigation into Membrane Bound Redox Carriers Involved in Energy Transduction Mechanism in Brevibacterium linens DSM 20158 with Unsequenced Genome
|
|---|---|
| Published in |
The Journal of Membrane Biology, February 2014
|
| DOI | 10.1007/s00232-014-9641-4 |
| Pubmed ID | |
| Authors |
Khadija Shabbiri, Catherine H. Botting, Ahmad Adnan, Matthew Fuszard, Shahid Naseem, Safeer Ahmed, Shahida Shujaat, Quratulain Syed, Waqar Ahmad |
| Abstract |
Brevibacterium linens (B. linens) DSM 20158 with an unsequenced genome can be used as a non-pathogenic model to study features it has in common with other unsequenced pathogens of the same genus on the basis of comparative proteome analysis. The most efficient way to kill a pathogen is to target its energy transduction mechanism. In the present study, we have identified the redox protein complexes involved in the electron transport chain of B. linens DSM 20158 from their clear homology with the shot-gun genome sequenced strain BL2 of B. linens by using the SDS-Polyacrylamide gel electrophoresis coupled with nano LC-MS/MS mass spectrometry. B. linens is found to have a branched electron transport chain (Respiratory chain), in which electrons can enter the respiratory chain either at NADH (Complex I) or at Complex II level or at the cytochrome level. Moreover, we are able to isolate, purify, and characterize the membrane bound Complex II (succinate dehydrogenase), Complex III (menaquinone cytochrome c reductase cytochrome c subunit, Complex IV (cytochrome c oxidase), and Complex V (ATP synthase) of B. linens strain DSM 20158. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 1 | 14% |
| Professor | 1 | 14% |
| Professor > Associate Professor | 1 | 14% |
| Researcher | 1 | 14% |
| Unknown | 3 | 43% |
| Readers by discipline | Count | As % |
|---|---|---|
| Unspecified | 1 | 14% |
| Biochemistry, Genetics and Molecular Biology | 1 | 14% |
| Agricultural and Biological Sciences | 1 | 14% |
| Chemistry | 1 | 14% |
| Unknown | 3 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2018.
All research outputs
#7,850,857
of 23,806,312 outputs
Outputs from The Journal of Membrane Biology
#169
of 803 outputs
Outputs of similar age
#74,955
of 222,593 outputs
Outputs of similar age from The Journal of Membrane Biology
#2
of 19 outputs
Altmetric has tracked 23,806,312 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 803 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
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We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.