Title |
Survival of Borrelia burgdorferi in antibiotically treated patients with lyme borreliosis
|
---|---|
Published in |
Infection, November 1989
|
DOI | 10.1007/bf01645543 |
Pubmed ID | |
Authors |
Vera Preac-Mursic, B. Wilske, B. Gross, K. Weber, H. W. Pfister, A. Baumann, J. Prokop |
Abstract |
The persistence of Borrelia burgdorferi in patients treated with antibiotics is described. The diagnosis of Lyme disease is based on clinical symptoms, epidemiology and specific IgG and IgM antibody titers to B. burgdorferi in serum. Antibiotic therapy may abrogate the antibody response to the infection as shown in our patients. B. burgdorferi may persist as shown by positive culture in MKP-medium; patients may have subclinical or clinical disease without diagnostic antibody titers to B. burgdorferi. We conclude that early stage of the disease as well as chronic Lyme disease with persistence of B. burgdorferi after antibiotic therapy cannot be excluded when the serum is negative for antibodies against B. burgdorferi. |
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France | 6 | 19% |
United Kingdom | 3 | 10% |
Canada | 1 | 3% |
Unknown | 14 | 45% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 24 | 77% |
Practitioners (doctors, other healthcare professionals) | 3 | 10% |
Science communicators (journalists, bloggers, editors) | 3 | 10% |
Unknown | 1 | 3% |
Mendeley readers
Geographical breakdown
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United Kingdom | 1 | 2% |
United States | 1 | 2% |
Unknown | 41 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 21% |
Other | 6 | 14% |
Student > Doctoral Student | 6 | 14% |
Student > Master | 5 | 12% |
Student > Bachelor | 4 | 9% |
Other | 9 | 21% |
Unknown | 4 | 9% |
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Agricultural and Biological Sciences | 7 | 16% |
Immunology and Microbiology | 6 | 14% |
Psychology | 2 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Other | 7 | 16% |
Unknown | 5 | 12% |