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Mendeley readers
Attention Score in Context
| Title |
Biosynthesis and insecticidal properties of plant cyclotides: The cyclic knotted proteins from Oldenlandia affinis
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, September 2001
|
| DOI | 10.1073/pnas.191366898 |
| Pubmed ID | |
| Authors |
Cameron Jennings, Jenny West, Clement Waine, David Craik, Marilyn Anderson |
| Abstract |
Several members of the Rubiaceae and Violaceae families produce a series of cyclotides or macrocyclic peptides of 29-31 amino acids with an embedded cystine knot. We aim to understand the mechanism of synthesis of cyclic peptides in plants and have isolated a cDNA clone that encodes the cyclotide kalata B1 as well as three other clones for related cyclotides from the African plant Oldenlandia affinis. The cDNA clones encode prepropeptides with a 20-aa signal sequence, an N-terminal prosequence of 46-68 amino acids and one, two, or three cyclotide domains separated by regions of about 25 aa. The corresponding cyclotides have been isolated from plant material, indicating that the cyclotide domains are excised and cyclized from all four predicted precursor proteins. The exact processing site is likely to lie on the N-terminal side of the strongly conserved GlyLeuPro or SerLeuPro sequence that flanks both sides of the cyclotide domain. Cyclotides have previously been assigned an antimicrobial function; here we describe a potent inhibitory effect on the growth and development of larvae from the Lepidopteran species Helicoverpa punctigera. |
Mendeley readers
The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | <1% |
| Australia | 1 | <1% |
| India | 1 | <1% |
| New Zealand | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 169 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 21% |
| Researcher | 24 | 14% |
| Student > Master | 18 | 10% |
| Student > Bachelor | 18 | 10% |
| Student > Postgraduate | 9 | 5% |
| Other | 28 | 16% |
| Unknown | 40 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 25% |
| Biochemistry, Genetics and Molecular Biology | 39 | 22% |
| Chemistry | 21 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
| Medicine and Dentistry | 6 | 3% |
| Other | 12 | 7% |
| Unknown | 47 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2023.
All research outputs
#1,388,543
of 25,837,817 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#19,288
of 103,917 outputs
Outputs of similar age
#954
of 42,842 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#24
of 488 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 103,917 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 39.6. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 42,842 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 488 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.