Title |
Genetics and Genomics of Social Behavior in a Chicken Model
|
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Published in |
Genetics, March 2018
|
DOI | 10.1534/genetics.118.300810 |
Pubmed ID | |
Authors |
Martin Johnsson, Rie Henriksen, Jesper Fogelholm, Andrey Höglund, Per Jensen, Dominic Wright |
Abstract |
The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identify genes for social reinstatement, a social and anxiety-related behavior. A total of 24 social reinstatement QTL were identified and overlaid with over 600 eQTL obtained from the same birds using hypothalamic tissue. Correlations between overlapping QTL and eQTL indicated 5 strong candidate genes, with the geneTTRAPbeing strongly significantly correlated with multiple aspects of social reinstatement behavior, as well as possessing a highly significant eQTL. |
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United States | 5 | 50% |
Sweden | 1 | 10% |
Spain | 1 | 10% |
Puerto Rico | 1 | 10% |
Unknown | 2 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 70% |
Scientists | 3 | 30% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 11 | 22% |
Student > Doctoral Student | 6 | 12% |
Student > Master | 6 | 12% |
Researcher | 6 | 12% |
Student > Bachelor | 4 | 8% |
Other | 9 | 18% |
Unknown | 8 | 16% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 19 | 38% |
Biochemistry, Genetics and Molecular Biology | 6 | 12% |
Neuroscience | 5 | 10% |
Veterinary Science and Veterinary Medicine | 4 | 8% |
Medicine and Dentistry | 2 | 4% |
Other | 3 | 6% |
Unknown | 11 | 22% |