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Structure and Function of Cholinesterases and Related Proteins

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Cover of 'Structure and Function of Cholinesterases and Related Proteins'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 1 Bert N. La Du, a Summary of His Career to 1998
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    Chapter 2 Diversity and Processing of Acetylcholinesterase
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    Chapter 3 Structural and Functional Studies on Acetylcholinesterase
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    Chapter 4 Genetic Manipulations of Catalytic and Non-Catalytic Functions of Human Cholinesterases
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    Chapter 5 ACHE Knockout Mouse; Cat AChE and Cat BChE Sequences; Tetramers of BChE
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    Chapter 6 Molecular Mechanisms Controlling the Synapse-Specific Expression and Activity-Linked Regulation of Acetylcholinesterase in Skeletal Muscle Fibers
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    Chapter 7 Intronic Elements Appear Essential for the Differentiation-Specific Expression of Acetylcholinesterase in C2C12 Myotubes
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    Chapter 8 The Building of Acetylcholinesterase Collagen-Tailed Forms
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    Chapter 9 Fluorescent Fasciculin
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    Chapter 10 Factors that Determine AChE Efficacy in Synaptic Function
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    Chapter 11 Glucocorticoid Control of Acetylcholinesterase and Butyrylcholinesterase Expression in the Mammalian Organism
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    Chapter 12 Four Acetylcholinesterase Genes in the Nematodes caenorhabditis Elegans and Caenorhabditis Briggsae
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    Chapter 13 Neural Activation of Muscles Regulates Muscle Acetylcholinesterase Expression
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    Chapter 14 Acetylcholinesterase in Elapid Snakes
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    Chapter 15 Structure and Function of Cholinesterases from Agnathans and Cephalochordates
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    Chapter 16 The Human Ache Locus Includes a Polymorphic Enhancer Domain 17KB Upstream from the Transcription Start Site
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    Chapter 17 Novel Transcription Start Site for Murine AChE
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    Chapter 18 Neurotrophins Differentially Regulate Expression of Cholinergic Enzymes in Cultured Spinal Cord Motoneurons
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    Chapter 19 Extrajunctional Expression of the Asymmetric Molecular Forms of Acetylcholinesterase in Slow Rat Muscles Transinnervated by a Fast Motor Nerve
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    Chapter 20 Increased Expression of Acetylcholinesterase T and R Transcripts During Hematopoietic Differentiation is Accompanied by Parallel Elevations in the Levels of Their Respective Molecular Forms
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    Chapter 21 Expression of the Acetylcholinesterase Gene in Skeletal Muscle Fibers
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    Chapter 22 Intronic Sequences Influence Pre-mRNA Splicing of Acetylcholinesterase During Muscle Differentiation
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    Chapter 23 Calcineurin Enhances mRNA Stability of Acetylcholinesterase During Muscle Differentiation in C2-C12 Cells
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    Chapter 24 Degradation of AChE mRNA in the Normal and Denervated Rat Skeletal Muscle
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    Chapter 25 Transcriptional Control of Acetylcholinesterase Expression During Quail Muscle Development in Culture
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    Chapter 26 Activity-Linked Regulation of Acetylcholinesterase mRNA Levels Involves Distinct Molecular Mechanisms in Developing Versus Adult Skeletal Muscles
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    Chapter 27 Testosterone Regulation of Acetylcholinesterase in the Rat Levator Ani Muscle
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    Chapter 28 Assembly, Stability and Secretion of Acetylcholinesterase in Cultured Mouse Muscle Cells
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    Chapter 29 Regulation of Acetylcholinesterase Oligomerization in the Muscles by Associated-Acetylcholinesterase Collagen, ColQ
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    Chapter 30 The Glycolipid-Addition Signal of Acetylcholinesterase
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    Chapter 31 Four Acetylcholinesterase Genes in the Nematode Caenorhabditis Elegans
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    Chapter 32 Four Acetylcholinesterase Genes in the Nematode Caenorhabditis Elegans
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    Chapter 33 cDNA Cloning, In Vitro Expression, and Biochemical Characterization of Cholinesterase 1 and Cholinesterase 2 from Amphioxus
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    Chapter 34 Acetylcholinesterase Expression During Development of Danio Rerio
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    Chapter 35 Molecular Cloning and Characterization of a cDNA Encoding AChE from Optic Lobe of Loligo Opalescences
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    Chapter 36 Electrophorus Electricus Acetylcholinesterase
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    Chapter 37 Amino Acid Sequence of Horse Serum Butyrylcholinesterase
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    Chapter 38 Acetylcholinesterase and Butyrylcholinesterase of Cat
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    Chapter 39 Bovine Acetylcholinestrase — Cloning, Expression and Characterization of the Recombinant Enzyme
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    Chapter 40 Acetylcholinesterase Autoimmunity In Vitro
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    Chapter 41 Expression of Human Butyrylcholinesterase in Trichoplusia ni Insect Larvae
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    Chapter 42 Stabilization of Recombinant Drosophila Acetylcholinesterase
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    Chapter 43 Pharmacological Basis of Cholinergic Therapy in Alzheimer Disease
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    Chapter 44 Age Influences the Synergy between Butyrylcholinesterase K Variant and Apolipoprotein E ε4 in Late-Onset Alzheimer’s Disease
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    Chapter 45 Molecular Interactions of Acetylcholinesterase with the Synaptic Basal Lamina and the Senile Plaques
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    Chapter 46 Expression and Glycosylation of Acetylcholinesterase in Alzheimer’s Disease Brain
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    Chapter 47 Comparative Effects of Cholinesterase Inhibitors on Glutamate-Induced Neuronal Cell Death
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    Chapter 48 Acetylcholinesterase Enhances the Neurotoxicity of β-Amyloid Fibrils
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    Chapter 49 Multilevel Approaches to AChE-Induced Impairments in Learning and Memory
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    Chapter 50 Identification of an Acetylcholinesterase Fragment that Promotes Alzheimer β-Amyloid Fibril Formation
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    Chapter 51 Differential Effect of Acetylcholinesterase on Neuronal and Glial Cells in Culture
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    Chapter 52 Substrate Binding to the Peripheral Site Occurs on the Catalytic Pathway of Acetylcholinesterase and Leads to Substrate Inhibition
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    Chapter 53 Structure of the Acylation Transition State for Acetylcholinesterase Catalysis
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    Chapter 54 Contribution of the Active Center Functional Architecture to AChE Reactivity Toward Substrates and Inhibitors
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    Chapter 55 The Effect of Peripheral Site Ligands on the Reaction Kinetics of Phosphyl and Carboxyl Esters with Acetylcholinesterase
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    Chapter 56 Acceleration of Oxime-Induced Reactivation of Organophosphate-Inhibited Acetylcholinesterase by Quaternary Ligands
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    Chapter 57 Reaction of Human Butyrylcholinesterase (BChE) H117 Enzymes with Carbamates
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    Chapter 58 An Integrated Model for the Molecular Traffic through the Active Site of Cholinesterases
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    Chapter 59 Substrate Binding to the Acetylcholinesterase Peripheral Site Promotes Substrate Hydrolysis but also Gives Rise to Substrate Inhibition
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    Chapter 60 Activity of Torpedo Californica Acetylcholinesterase in the Crystalline State
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    Chapter 61 Correlation of Isotope and Viscosity Effects
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    Chapter 62 Low-Barrier Hydrogen Bond in the Catalytic Triad of Serine Enzymes
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    Chapter 63 Does Electrostatic Attraction or Steering by Charged Residues within the Gorge Contribute to the Reactivity of AChE?
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    Chapter 64 Photoaffinity Labeling with [ 3 H]-DDF Reveals TRP82 and TYR332 are Involved in Two Quaternary Ammonium Binding Domains of Human Butyrylcholinesterase
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    Chapter 65 4-Aminoquinolines as AChE Inhibitors
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    Chapter 66 Identification of Residues Involved in Naja Naja Oxiana AChE Insensitivity to Fasciculin
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    Chapter 67 Expression and Purification of Recombinant Mutants of Fasciculin from Mammalian Cells
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    Chapter 68 Photo-Induced Inhibition of Human Butyrylcholinesterase by Phenyldiazonium Esters
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    Chapter 69 Inhibition of Acetylcholinesterase (ACHE; E.C. 3.1.1.7) and Butyrylcholinesterase (BCHE; E.C. 3.1.1.8) by Terbutaline
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    Chapter 70 Effects of Triton X100 on the Activity of Acetylcholinesterases from Drosophila Melanogaster, Musca Domestica and Torpedo Californica
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    Chapter 71 Cyclic, Selectively Permeable Acetylcholinesterase Inhibitors
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    Chapter 72 The Aromatic Moiety at Position-86 of HuAChE Accelerate the Aging of Phosphonyl-AChE Conjugates through Cation-π Interactions
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    Chapter 73 pH Dependence of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants
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    Chapter 74 ESMS as a Unique Tool for the Molecular Monitoring of Reactions between HuAChE and Various OP-Agents
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    Chapter 75 Reactivation of Enantiomeric Organophosphonyl Conjugates of Acetylcholinesterase Mutants, F295L and F297I by Mono- and Bis-Quarternary Oximes
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    Chapter 76 Improved Acetylcholinesterase Reactivation with Bis-Oximes Modeled on Crystal Structure
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    Chapter 77 Caged Cholinergic Ligands and Photoregulation of Cholinesterase Activities
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    Chapter 78 Current Capabilities in Extrapolating from Animal to Human the Capacity of Human Butyrylcholinesterase to Detoxify Organophosphates
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    Chapter 79 Retrospective Detection of Exposure to Nerve Agents in the Rhesus Monkey and in Man
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    Chapter 80 Acetylcholinesterase, a Versatile Protein
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    Chapter 81 Quaternary-Lipophilic Carbamates with Blood Brain Barrier Permeability as Potential Drugs for the Treatment of Diseases Associated with Cholinergic Deficiency
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    Chapter 82 The Role of Oligosaccharides in the Pharmacokinetics of Cholinesterases
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    Chapter 83 Contribution of Primary Sequence and Post-Translation Modification to the Pharmacokinetics of Human and Bovine Acetylcholinesterases
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    Chapter 84 Synthesis of Imidazolio-Quinuclidinium Oximes
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    Chapter 85 A Comparison of Blood Cholinesterase Activities, Pyridostigmine Inhibition of Red Cell Acetylcholinesterase, and Butyrylcholinesterase Phenotypes in Gulf War Veterans and Normal Controls
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    Chapter 86 Blood Cholinesterase Activity Levels of Victims Intoxicated with Sarin in Matsumoto and Tokyo Subway System
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    Chapter 87 Diisopropylphosphorofluoridate-Induced Modulation of Different Nerve Action Potentials
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    Chapter 88 Sequestration of Toxic Phosphorylated Oximes by Stoichiometric and Catalytic Scavengers
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    Chapter 89 Characterization of ChEs Immobilized on Polyurethane Foams
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    Chapter 90 Structure-Function Relationships in High Molecular Weight PAF-Acetylhydrolases from the Studies of a Microbial α/β Hydrolase
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    Chapter 91 Crystal Structure of Mouse Acetylcholinesterase
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    Chapter 92 3D Structure at 2.7 Å Resolution of Native and E202Q Mutant Human Acetylcholinesterase Complexed with Fasciculin-II
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    Chapter 93 Computer Simulation Studies of Acetylcholinesterase Dynamics and Activity
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    Chapter 94 Fasciculin Inhibition of Mouse Acetylcholinesterase
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    Chapter 95 The Push-Pull Mechanism of Dealkylation in Soman-Inhibited Cholinesterases and Their Mutants
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    Chapter 96 Thermodynamic Correlation with Kinetic Association Rates for Several Mutants of Mouse Acetylcholinesterase
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    Chapter 97 Quaternary Structure of Tetrameric Acetylcholinesterase
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    Chapter 98 Fast Molecular Docking Methods
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    Chapter 99 Weighted-Ensemble Brownian Dynamics for Charged Ligand Diffusion onto Acetylcholinesterase
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    Chapter 100 Alternate Pathways for Acetic Acid and Acetate Ion Release from Acetylcholinesterase
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    Chapter 101 Molecular Dynamics of Acetylcholinesterase Dimer
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    Chapter 102 3D Structure of a Complex of Human Acetylcholinesterase with Fasciculin-II at 2.7 Å Resolution
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    Chapter 103 Crystal Structures of Complexes of E2020-Related Compounds with Torpedo Californica Acetylcholinesterase
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    Chapter 104 Alternative Crystal Forms of Torpedo Californica Acetylcholinesterase
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    Chapter 105 Kinetic and X-Ray Crystallographic Studies of the Binding of ENA-713 to Torpedo Californica Acetylcholinesterase
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    Chapter 106 Compatibility of Structures Inferred from Mutagenesis and from X-Ray Crystallography for Various AChE Complexes
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    Chapter 107 Oxime Reactivation of Acetylcholinesterase Inhibited by Enantiomeric Organophosphates
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    Chapter 108 Site-Directed Photo-Probes for Structural and Functional Investigations on Cholinesterases
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    Chapter 109 Comparison of Cholinesterases and Carboxylesterase as Bioscavengers for Organophosphorus Compounds
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    Chapter 110 Optimization of the Signal Peptide for Glycosyl Phosphatidylinositol-(GPI)-Modification of Human Acetylcholinesterase
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    Chapter 111 Mechanical Aspects of the Phosphotriesterase Activity of Human Butyrylcholinesterase G117H Mutant
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    Chapter 112 Metal Binding Motifs in Cholinesterases and Neuroligins
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    Chapter 113 A View from the Gorge
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    Chapter 114 Structural Changes in the Active Site Gorge of Phosphylated Cholinesterase Accompanying the Aging Process
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    Chapter 115 Crystal Structures of “Aged” Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase
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    Chapter 116 On the Mechanisms of Anticholinesterase Action of Organophosphorus Inhibitors (OPI)
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    Chapter 117 Mechanical Aspects of the Phosphotriesterase Activity of Human Butyrylcholinesterase G117H Mutant
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    Chapter 118 Surface Residues Near the Peripheral Site Affect the Stability of Torpedo Acetylcholinesterase
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    Chapter 119 Stability of the Quaternary Structure of Butyrylcholinesterase Subjected to Ultrasound or Hydrostatic Pressure
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    Chapter 120 Membrane-Promoted Unfolding of Torpedo Californica and Bungarus Fasciatus Acetylcholinesterase
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    Chapter 121 Association of Tetramers of Human Butyrylcholinesterase is Mediated by Conserved Aromatic Residues of the Carboxy Terminus
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    Chapter 122 Assembly of Acetylcholinesterase Subunits in vitro
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    Chapter 123 The Heparin-Binding Sites in the Collagenic Tail of Acetylcholinesterase
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    Chapter 124 The Heparin-Binding Sites in the Collagenic Tail of Acetylcholinesterase
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    Chapter 125 The Conjunction of a Conserved Electrostatic Motif and a Common Cholinesterase Fold Defines a Class of Adhesion Proteins
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    Chapter 126 Expression and Tissue Distribution of Cholinesterases Via EST Analysis
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    Chapter 127 Homology Modelling of Drosophila Melanogaster and Electrophorus Eel Acetylcholinesterases
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    Chapter 128 Acetylcholinesterase Structural Perturbations Examined Through Cysteine Substitution Mutagenesis
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    Chapter 129 Structural Modifications of the Ω Loop in Human Acetylcholinesterase
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    Chapter 130 Crystal Structures of “Aged” Phosphorylated and Phosphonylated Torpedo Californica Acetylcholinesterase
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    Chapter 131 A Database of Pairwise Aligned 3-D Structures for the Acetylcholinesterases, Lipases and Other Homologous Proteins
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    Chapter 132 ESTHER 1998, aChEdb Short Tutorial
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    Chapter 133 3D Structure of a Complex of the Anti-Alzheimer Drug, E2020, with Acetylcholinesterase at 2.5Å Resolution
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    Chapter 134 The OECD Program: Biological Resource Management for Sustainable Agricultural Systems
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    Chapter 135 Researches on Cholinesterases and Plant Protection
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    Chapter 136 Acetylcholinesterase and Insecticide Resistance in the Mosquito Culex Pipiens
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    Chapter 137 Biochemical and Molecular Characterisation of Insecticide Insensitive Acetylcholinesterase in Resistant Insects
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    Chapter 138 Molecular Basis of Esterase-Mediated OP Resistance in Two Higher Diptera
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    Chapter 139 Acetylcholinesterase Increase in Drosophila as a Mechanism of Resistance to Insecticide
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    Chapter 140 Why do Some Parasitic Nematodes Secrete Acetylcholinesterase (ACHE)?
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    Chapter 141 Secretory Acetylcholinesterases from the Nematode Parasite Nippostrongylus Brasiliensis
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    Chapter 142 Differential Plant-Parasitic Nematode Sensitivity to Acetylcholinesterase Inhibitors
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    Chapter 143 Isomalathion Stereoisomers
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    Chapter 144 Cholinesterases and Agriculture
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    Chapter 145 Purification and Biochemical Characterization of Affinity-Tagged Musca Domestica Acetylcholinesterase Secreted from Baculovirus Infected Cells
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    Chapter 146 Mutations in the Housefly Acetylcholinesterase Gene that Confer Resistance to Insecticides
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    Chapter 147 An Insensitive ACHE Confers Insecticide Resistance in Myzus Persicae
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    Chapter 148 The Acetylcholinesterase Gene and Organophosphorous Resistance in the Australian Sheep Blowfly, Lucilia Cuprina
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    Chapter 149 Shielding of Acetylcholinesterase does not Result in the Protection of Honey Bee against Poisoning by Organophosphates
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    Chapter 150 Engineering Sensitive Acetylcholinesterase for Detection of Organophosphate and Carbamate Insecticides
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    Chapter 151 Comparison of Fetal and Maternal Brain Cholinesterase Activity Following Repeated Versus Single Late Gestational Exposure to Chlorpyrifos
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    Chapter 152 Non-Cholinergic Actions of Acetylcholinesterase in the Substantia Nigra
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    Chapter 153 Possible Adhesive Function of Transiently Expressed Acetylcholinesterase in Developing Cerebral Cortex
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    Chapter 154 Nonenzymatic Roles of Cholinesterases in Avian Neurogenesis
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    Chapter 155 A Morphogenic Role for Acetylcholinesterase in Neurite Outgrowth
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    Chapter 156 Pharmacologic Tests of a Role for Acetylcholinesterase in Promoting Neurite Outgrowth by Dorsal Root Ganglia
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    Chapter 157 Suppression of Butyrylcholinesterase Induces Overexpression of Acetylcholinesterase and Increased Apoptosis in Embryonic Chick Retinospheroids
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    Chapter 158 The Role of Acetylcholinesterase in Neuronal Differentiation
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    Chapter 159 Cholinesterase Activities in Intact Human Pulmonary Vessels Treated with LTD 4
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    Chapter 160 Increase of Cholinesterase Activity in Intact Human Bronchial Preparations Treated with Indomethacin
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    Chapter 161 Studies on a Molecular Form (C 4/5 ) of Human Butyrylcholinesterase (BChE)
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    Chapter 162 Frequency of the F2 Mutation of Human Butyrylcholinesterase in a Random Population Sample from Southern Brazil
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    Chapter 163 Frequencies of the Butyrylcholinesterase K Mutation in Southern Brazilian Population Samples of European and African Origin
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    Chapter 164 The Relation of Nutrition Index (NI) with the C 4/5 Molecular Form of Butyrylcholinesterase (BChE) in Human Adults
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Title
Structure and Function of Cholinesterases and Related Proteins
Published by
Springer, Boston, MA, November 2013
DOI 10.1007/978-1-4899-1540-5
ISBNs
978-1-4899-1542-9, 978-1-4899-1540-5
Editors

Bhupendra P. Doctor, Palmer Taylor, Daniel M. Quinn, Richard L. Rotundo, Mary K. Gentry

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Geographical breakdown

Country Count As %
United States 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 21%
Student > Bachelor 1 7%
Student > Master 1 7%
Unknown 9 64%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 21%
Biochemistry, Genetics and Molecular Biology 1 7%
Chemistry 1 7%
Unknown 9 64%