| Title |
Retardation of myelination due to dietary vitamin B12 deficiency: cranial MRI findings
|
|---|---|
| Published in |
Pediatric Radiology, February 1997
|
| DOI | 10.1007/s002470050090 |
| Pubmed ID | |
| Authors |
Karl-Olof Lövblad, Gianpaolo Ramelli, Luca Remonda, Arto C. Nirkko, Christoph Ozdoba, Gerhard Schroth |
| Abstract |
Vitamin B12 deficiency is known to be associated with signs of demyelination, usually in the spinal cord. Lack of vitamin B12 in the maternal diet during pregnancy has been shown to cause severe retardation of myelination in the nervous system. We report the case of a 14(1)/2-month-old child of strictly vegetarian parents who presented with severe psychomotor retardation. This severely hypotonic child had anemia due to insufficient maternal intake of vitamin B12 with associated megaloblastic anemia. MRI of the brain revealed severe brain atrophy with signs of retarded myelination, the frontal and temporal lobes being most severely affected. It was concluded that this myelination retardation was due to insufficient intake of vitamin B12 and vitamin B12 therapy was instituted. The patient responded well with improvement of clinical and imaging abnormalities. We stress the importance of MRI in the diagnosis and follow-up of patients with suspected diseases of myelination. |
X Demographics
The data shown below were collected from the profiles of 219 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 40 | 18% |
| Chile | 9 | 4% |
| Japan | 7 | 3% |
| United States | 6 | 3% |
| United Kingdom | 4 | 2% |
| Germany | 3 | 1% |
| Nicaragua | 2 | <1% |
| Argentina | 2 | <1% |
| Italy | 1 | <1% |
| Other | 6 | 3% |
| Unknown | 139 | 63% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 213 | 97% |
| Practitioners (doctors, other healthcare professionals) | 3 | 1% |
| Science communicators (journalists, bloggers, editors) | 2 | <1% |
| Scientists | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Germany | 1 | <1% |
| Australia | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 121 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 20 | 16% |
| Student > Bachelor | 19 | 15% |
| Student > Ph. D. Student | 12 | 10% |
| Student > Postgraduate | 11 | 9% |
| Other | 8 | 6% |
| Other | 26 | 21% |
| Unknown | 29 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 21% |
| Agricultural and Biological Sciences | 13 | 10% |
| Nursing and Health Professions | 11 | 9% |
| Neuroscience | 9 | 7% |
| Psychology | 7 | 6% |
| Other | 23 | 18% |
| Unknown | 36 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 181. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2023.
All research outputs
#225,902
of 25,757,133 outputs
Outputs from Pediatric Radiology
#1
of 2,259 outputs
Outputs of similar age
#115
of 94,383 outputs
Outputs of similar age from Pediatric Radiology
#1
of 5 outputs
Altmetric has tracked 25,757,133 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,259 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 99% of its peers.
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We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them