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Stability of alcohol and tobacco consumption biomarkers in a real rising main sewer

Overview of attention for article published in Water Research, March 2018
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Title
Stability of alcohol and tobacco consumption biomarkers in a real rising main sewer
Published in
Water Research, March 2018
DOI 10.1016/j.watres.2018.03.036
Pubmed ID
Authors

Jianfa Gao, Jiaying Li, Guangming Jiang, Zhiguo Yuan, Geoff Eaglesham, Adrian Covaci, Jochen F. Mueller, Phong K. Thai

Abstract

Since alcohol and tobacco consumption are among the leading causes of population health harm, it is very important to understand the consumption behaviour to develop effective harm reduction strategies. Wastewater-based epidemiology (WBE) is a potential tool for estimating their consumption, but there are several uncertainties that need to be determined, including the stability of biomarkers in the sewer. Utilizing a real rising main sewer, this study investigated the stability of alcohol and tobacco consumption biomarkers. Rhodamine and acesulfame were used as flow tracer and benchmarker to understand the transportation of wastewater in the sewer with a hydraulic retention time between 2.7 and 5.0 h. Ethyl sulphate (EtS) and ethyl glucuronide (EtG), two biomarkers of alcohol consumption, were found to have different in-sewer stability, with EtS much more stable than EtG. The degradation rate of EtS is approximately 8% per hour, while EtG has a half-life of 1.9 h. Formation of nicotine, cotinine and trans-3'-hydroxycotinine, three biomarkers for tobacco consumption, was observed during the experiment, probably due to deconjugation of their glucuronide chemicals. The deconjugation process has prevented the determination of actual stability of the three chemicals. However, it is suggested that cotinine is relatively stable, while nicotine and trans-3'-hydroxycotinine degrade to a certain degree in the sewer system. According to our findings, the in-sewer degradation is more important during the interpretation of alcohol consumption estimation than for tobacco consumption estimation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 14%
Student > Ph. D. Student 7 12%
Student > Master 5 9%
Professor 4 7%
Student > Bachelor 3 5%
Other 10 18%
Unknown 20 35%
Readers by discipline Count As %
Environmental Science 7 12%
Engineering 7 12%
Chemistry 5 9%
Medicine and Dentistry 3 5%
Unspecified 2 4%
Other 3 5%
Unknown 30 53%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2018.
All research outputs
#14,920,631
of 25,382,440 outputs
Outputs from Water Research
#5,812
of 11,877 outputs
Outputs of similar age
#181,855
of 351,830 outputs
Outputs of similar age from Water Research
#105
of 241 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,877 research outputs from this source. They receive a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,830 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 241 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.