| Title |
Novel strategies in tendon and ligament tissue engineering: Advanced biomaterials and regeneration motifs
|
|---|---|
| Published in |
BMC Sports Science, Medicine and Rehabilitation, August 2010
|
| DOI | 10.1186/1758-2555-2-20 |
| Pubmed ID | |
| Authors |
Catherine K Kuo, Joseph E Marturano, Rocky S Tuan |
| Abstract |
Tendon and ligaments have poor healing capacity and when injured often require surgical intervention. Tissue replacement via autografts and allografts are non-ideal strategies that can lead to future problems. As an alternative, scaffold-based tissue engineering strategies are being pursued. In this review, we describe design considerations and major recent advancements of scaffolds for tendon/ligament engineering. Specifically, we outline native tendon/ligament characteristics critical for design parameters and outcome measures, and introduce synthetic and naturally-derived biomaterials used in tendon/ligament scaffolds. We will describe applications of these biomaterials in advanced tendon/ligament engineering strategies including the utility of scaffold functionalization, cyclic strain, growth factors, and interface considerations. The goal of this review is to compile and interpret the important findings of recent tendon/ligament engineering research in an effort towards the advancement of regenerative strategies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 240 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| United Kingdom | 3 | 1% |
| Australia | 1 | <1% |
| Switzerland | 1 | <1% |
| Canada | 1 | <1% |
| France | 1 | <1% |
| Unknown | 228 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 56 | 23% |
| Student > Master | 37 | 15% |
| Student > Bachelor | 36 | 15% |
| Researcher | 27 | 11% |
| Other | 14 | 6% |
| Other | 41 | 17% |
| Unknown | 29 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 48 | 20% |
| Agricultural and Biological Sciences | 47 | 20% |
| Medicine and Dentistry | 43 | 18% |
| Biochemistry, Genetics and Molecular Biology | 23 | 10% |
| Chemistry | 12 | 5% |
| Other | 24 | 10% |
| Unknown | 43 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2015.
All research outputs
#15,321,186
of 22,787,797 outputs
Outputs from BMC Sports Science, Medicine and Rehabilitation
#351
of 497 outputs
Outputs of similar age
#76,820
of 94,946 outputs
Outputs of similar age from BMC Sports Science, Medicine and Rehabilitation
#5
of 6 outputs
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