| Title |
Tremor in multiple sclerosis
|
|---|---|
| Published in |
Journal of Neurology, February 2007
|
| DOI | 10.1007/s00415-006-0296-7 |
| Pubmed ID | |
| Authors |
Marcus Koch, Jop Mostert, Dorothea Heersema, Jacques De Keyser |
| Abstract |
Tremor is estimated to occur in about 25 to 60 percent of patients with multiple sclerosis (MS). This symptom, which can be severely disabling and embarrassing for patients, is difficult to manage. Isoniazid in high doses, carbamazepine, propranolol and gluthetimide have been reported to provide some relief, but published evidence of effectiveness is very limited. Most trials were of small size and of short duration. Cannabinoids appear ineffective. Tremor reduction can be obtained with stereotactic thalamotomy or thalamic stimulation. However, the studies were small and information on long-term functional outcome is scarce. Physiotherapy, tremor reducing orthoses, and limb cooling can achieve some functional improvement. Tremor in MS remains a significant challenge and unmet need, requiring further basic and clinical research. |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 1% |
| Brazil | 2 | 1% |
| Iran, Islamic Republic of | 2 | 1% |
| Italy | 1 | <1% |
| South Africa | 1 | <1% |
| United Kingdom | 1 | <1% |
| France | 1 | <1% |
| India | 1 | <1% |
| Japan | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 139 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 15% |
| Student > Master | 22 | 15% |
| Student > Bachelor | 19 | 13% |
| Other | 13 | 9% |
| Student > Doctoral Student | 12 | 8% |
| Other | 35 | 23% |
| Unknown | 27 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 54 | 36% |
| Neuroscience | 21 | 14% |
| Engineering | 11 | 7% |
| Agricultural and Biological Sciences | 5 | 3% |
| Biochemistry, Genetics and Molecular Biology | 4 | 3% |
| Other | 21 | 14% |
| Unknown | 35 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 January 2022.
All research outputs
#4,606,084
of 22,818,766 outputs
Outputs from Journal of Neurology
#1,180
of 4,475 outputs
Outputs of similar age
#14,268
of 76,246 outputs
Outputs of similar age from Journal of Neurology
#4
of 32 outputs
Altmetric has tracked 22,818,766 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,475 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 76,246 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.