Title |
Virotherapy of the Malignant U87 Human Glioblastoma in the Orthotopic Xenotransplantation Mouse SCID Model
|
---|---|
Published in |
Doklady Biochemistry and Biophysics, March 2018
|
DOI | 10.1134/s1607672918010088 |
Pubmed ID | |
Authors |
S. N. Shchelkunov, I. A. Razumov, I. V. Kolosova, A. V. Romashchenko, E. L. Zavjalov |
Abstract |
The possibility of glioblastoma virotherapy at intravenous injection of the LIVP-GFP recombinant virus was studied in experimental model of orthotopic xenotransplantation of human glioblastoma cell line U87 to SCID laboratory mice. The LIVP-GFP recombinant virus deficient for thymidine kinase exhibited a significantly greater oncolytic capacity than the original LIVP virus, and an intravenous injection of LIVP-GFP at the early stages of tumorigenesis in mouse brain in most cases resulted in the lysis of the tumor. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 17% |
Student > Bachelor | 1 | 17% |
Researcher | 1 | 17% |
Unknown | 3 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 1 | 17% |
Psychology | 1 | 17% |
Medicine and Dentistry | 1 | 17% |
Unknown | 3 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2018.
All research outputs
#19,512,854
of 24,003,070 outputs
Outputs from Doklady Biochemistry and Biophysics
#126
of 267 outputs
Outputs of similar age
#262,692
of 336,978 outputs
Outputs of similar age from Doklady Biochemistry and Biophysics
#2
of 4 outputs
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So far Altmetric has tracked 267 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
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