Title |
Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children
|
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Published in |
Journal of Autism and Developmental Disorders, March 2018
|
DOI | 10.1007/s10803-018-3537-6 |
Pubmed ID | |
Authors |
MacKinsey A. Christian, Maureen Samms-Vaughan, MinJae Lee, Jan Bressler, Manouchehr Hessabi, Megan L. Grove, Sydonnie Shakespeare-Pellington, Charlene Coore Desai, Jody-Ann Reece, Katherine A. Loveland, Eric Boerwinkle, Mohammad H. Rahbar |
Abstract |
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with poorly understood etiology. Many maternal exposures during pregnancy and breastfeeding potentially interfere with neurodevelopment. Using data from two age- and sex-matched case-control studies in Jamaica (n = 298 pairs), results of conditional logistic regression analyses suggest that maternal exposures to fever or infection (matched odds ratio (MOR) = 3.12, 95% CI 1.74-5.60), physical trauma (MOR 2.02, 95% CI 1.01-4.05), and oil-based paints (MOR 1.99, 95% CI 1.14-3.46) may be associated with ASD. Additionally, maternal exposure to oil-based paints may modify the relationship between maternal exposure to pesticides and ASD, which deepens our understanding of the association between pesticides and ASD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 17% |
United Kingdom | 2 | 17% |
Venezuela, Bolivarian Republic of | 1 | 8% |
Spain | 1 | 8% |
France | 1 | 8% |
Unknown | 5 | 42% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 10 | 83% |
Practitioners (doctors, other healthcare professionals) | 2 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 116 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 14% |
Student > Ph. D. Student | 14 | 12% |
Student > Doctoral Student | 11 | 9% |
Student > Bachelor | 10 | 9% |
Researcher | 10 | 9% |
Other | 11 | 9% |
Unknown | 44 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 16% |
Psychology | 16 | 14% |
Nursing and Health Professions | 12 | 10% |
Biochemistry, Genetics and Molecular Biology | 5 | 4% |
Neuroscience | 4 | 3% |
Other | 15 | 13% |
Unknown | 46 | 40% |