| Title |
Body mass index and the all-cause mortality rate in patients with type 2 diabetes mellitus
|
|---|---|
| Published in |
Acta Diabetologica, March 2018
|
| DOI | 10.1007/s00592-018-1126-y |
| Pubmed ID | |
| Authors |
Rezvan Salehidoost, Asieh Mansouri, Massoud Amini, Sima Aminorroaya Yamini, Ashraf Aminorroaya |
| Abstract |
The relationship between obesity and mortality rate among diabetic patients is a controversial topic. The aim of this study was to investigate the association between obesity and all-cause mortality risk in patients with type 2 diabetes. In this retrospective database study, 2383 patients with type 2 diabetes, who had been registered in the Isfahan Endocrine and Metabolism Research Center, Iran, were enrolled between 1992 and 2010. The mean (SD) of diabetes duration and follow-up period was 15.5 (8.0) and 7.8 (3.9) years. The main outcome was all-cause mortality. All-cause mortality rates were calculated for the body mass index (BMI) categories of underweight, normal, overweight and class I, II and III obese. Cox proportional hazard models were used to estimate the adjusted hazard ratio for BMI as categorical variable using BMI of 18.5-24.9 kg/m2as the reference group. The mortality rate in patients with normal weight was higher than overweight patients (59.11 vs. 33.17 per 1000 person-years). The adjusted hazard ratios of all-cause mortality were 0.82 [95%CI 0.68-0.99; P = 0.037], 0.79 [95%CI 0.61-1.02; P = 0.069], 0.71 [95%CI 0.42-1.19; P = 0.191] and 1.36 [95%CI 0.55-3.33; P = 0.507] for overweight, class I, II and III obesity, respectively. When BMI was included in the Cox model as a time-dependent variable, the U-shaped relationship between BMI and all-cause mortality did not change. The results show a U-shaped association of BMI with all-cause mortality in patients with type 2 diabetes with the lowest risk observed among the overweight patients. |
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 15% |
| Researcher | 4 | 12% |
| Student > Master | 3 | 9% |
| Librarian | 2 | 6% |
| Student > Bachelor | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 16 | 47% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 35% |
| Nursing and Health Professions | 2 | 6% |
| Veterinary Science and Veterinary Medicine | 1 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Economics, Econometrics and Finance | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 16 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2018.
All research outputs
#18,591,506
of 23,028,364 outputs
Outputs from Acta Diabetologica
#657
of 931 outputs
Outputs of similar age
#259,435
of 333,790 outputs
Outputs of similar age from Acta Diabetologica
#15
of 26 outputs
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