| Title |
Immunoperoxidase staining of simple nuclear bodies in subacute sclerosing panencephalitis (SSPE) by antiserum to measles nucleocapsids
|
|---|---|
| Published in |
Acta Neuropathologica, September 1976
|
| DOI | 10.1007/bf00685370 |
| Pubmed ID | |
| Authors |
Hannah R. Brown, Halldor Thormar |
| Abstract |
Nuclear bodies have been found with great consistency in brain tissue from patients with subacute sclerosing panencephalitis (SSPE). There has been controversy as to the significance of these structures and their relationship, if any, to the disease. In this study, a non-productive, cell-associated strain of SSPE measles virus grown in tissue culture on Vero cells showed the continued presence of nuclear bodies, frequently in close association with the continued presence of nuclear bodies, frequently in close association with the SSPE measles virus nucleocapsids. Immunoperoxidase (I-P) staining with specific antiserum against measles virus nucleocapsids was done. The resultant positive labeling of the nuclear bodies demonstrates that they contain measles virus antigen and suggests that the nuclear bodies play a role in the development of the measles virus nucleocapsids of SSPE. |
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2013.
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#8,535,472
of 25,374,647 outputs
Outputs from Acta Neuropathologica
#1,519
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#1,125
of 4,644 outputs
Outputs of similar age from Acta Neuropathologica
#3
of 6 outputs
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