This retrospective study was designed to investigate the sole influence of orthokeratology (OK) lens fitting decentration on the Zernike coefficients of the reshaped anterior corneal surface.
This study comprised a review of 106 right eyes and measurements of corneal topography both before OK and at 1-month follow-up visit. A routine was designed to calculate local corneal surface astigmatism and assist the determination of OK lens fitting decentration from pupil center. The pupil-centered corneal Zernike coefficients of baseline (PCCB) and post-treatment (PCCP) were calculated. Meanwhile, the OK-lens-centered corneal Zernike coefficients of post-treatment (OCCP) were also calculated and considered as the presumptive ideal fitting group without decentration. Relationships between lens fitting decentration and the change of Zernike coefficients including (PCCP - PCCB) and (PCCP - OCCP) were analyzed.
Patients with a mean age of 11 ± 2.36 years old had an average spherical equivalent refractive error of -3.52 ± 1.06 D before OK. One month after treatment, OK lens fitting decentration from pupil center was 0.68 ± 0.35 mm. RMS of 3rd-order (P < 0.05), RMS of 4th-order (P < 0.001) and RMS of total high order (P < 0.001) corneal Zernike coefficients were increased in PCCP by comparing with OCCP, which was solely caused by lens fitting decentration. Nevertheless, no significant difference was observed in [Formula: see text] (P > 0.05). For the high order corneal Zernike coefficients in (PCCP - OCCP), radial distance of decentration was correlated with [Formula: see text] (r = -0.296, P < 0.05), [Formula: see text] (r = -0.396, P < 0.001), and [Formula: see text] (r = 0.449, P < 0.001), horizontal decentration was significantly correlated with [Formula: see text] (r = 0.901, P < 0.001) and [Formula: see text] (r = 0.340, P < 0.001), and vertical decentration was significantly correlated with [Formula: see text] (r = 0.904, P < 0.001).
OK lens fitting decentration within 1.5 mm hardly influenced the change of corneal spherical power for myopia correction, but significantly induced additional corneal high order Zernike coefficients including [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text].