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Mendeley readers
Attention Score in Context
| Title |
Cdx2 is essential for axial elongation in mouse development
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, May 2004
|
| DOI | 10.1073/pnas.0401654101 |
| Pubmed ID | |
| Authors |
Kallayanee Chawengsaksophak, Wim de Graaff, Janet Rossant, Jacqueline Deschamps, Felix Beck |
| Abstract |
Inactivation of Cdx2 leads to preimplantation embryonic lethality. Rescue of the implantation defect by tetraploid fusion established that Cdx2 is necessary for trophoblastic development, vasculogenesis in the yolk sac mesoderm, allantoic growth, and chorioallantoic fusion. "Rescued" Cdx2 mutants die at late gastrulation stages because of failure of placental development. Cdx2 is also needed for the completion of the normal process of gastrulation and tail bud elongation. Presegmental paraxial mesoderm is severely restricted in amount and somites posterior to somite 5 are abnormal. The Cdx2 mutation, like mutations impairing Wnt and Fgf signaling, causes posterior truncations and disturbs axial patterning of the embryonic structures, indicated by changes in the Hox expression domains. The gene appears to be important in the integration of the pathways controlling embryonic axial elongation, and anterior-posterior patterning. |
Mendeley readers
The data shown below were compiled from readership statistics for 210 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Germany | 1 | <1% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Portugal | 1 | <1% |
| Brazil | 1 | <1% |
| Norway | 1 | <1% |
| Japan | 1 | <1% |
| Sweden | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 200 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 59 | 28% |
| Researcher | 51 | 24% |
| Student > Master | 17 | 8% |
| Student > Bachelor | 16 | 8% |
| Professor > Associate Professor | 13 | 6% |
| Other | 31 | 15% |
| Unknown | 23 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 99 | 47% |
| Biochemistry, Genetics and Molecular Biology | 54 | 26% |
| Medicine and Dentistry | 15 | 7% |
| Engineering | 6 | 3% |
| Computer Science | 2 | <1% |
| Other | 8 | 4% |
| Unknown | 26 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 March 2019.
All research outputs
#3,914,244
of 24,625,114 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#36,641
of 101,438 outputs
Outputs of similar age
#6,046
of 61,279 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#130
of 633 outputs
Altmetric has tracked 24,625,114 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 101,438 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.8. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 61,279 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 633 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.