| Title |
Prothymosin α gene in humans: organization of its promoter region and localization to chromosome 2
|
|---|---|
| Published in |
Human Genetics, February 1993
|
| DOI | 10.1007/bf00202480 |
| Pubmed ID | |
| Authors |
P. Szabo, C. Panneerselvam, M. Clinton, M. Frangou-Lazaridis, D. Weksler, E. Whittington, M. J. Macera, K.-H. Grzeschik, A. Selvakumar, B. L. Horecker |
| Abstract |
A genomic clone encoding prothymosin alpha (gene symbol: PTMA), a nuclear-targeted protein associated with cell proliferation, was isolated and the 5'-regulatory region subcloned and sequenced. Because of previously reported discrepancies between several cDNA clones and a genomic clone for prothymosin alpha, we determined the sequence of the first exon and of a 1.7-kb region 5' to the first exon. The sequence of the genomic clone reported here corresponds to the published cDNA sequences, suggesting that the previously noted discrepancies may be due to genetic polymorphism in this region. In addition, our sequence data extend the known 5'-upstream sequence by an additional 1.5 kb allowing the identification of numerous, potential cis-acting regulatory sites. This 5'-flanking cloned probe permitted us to localize the prothymosin gene to chromosome 2 in humans. |
Mendeley readers
The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 1 | 25% |
| Other | 1 | 25% |
| Student > Postgraduate | 1 | 25% |
| Unknown | 1 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 1 | 25% |
| Agricultural and Biological Sciences | 1 | 25% |
| Immunology and Microbiology | 1 | 25% |
| Unknown | 1 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2020.
All research outputs
#7,453,827
of 22,788,370 outputs
Outputs from Human Genetics
#933
of 2,953 outputs
Outputs of similar age
#13,102
of 65,222 outputs
Outputs of similar age from Human Genetics
#4
of 14 outputs
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