| Title |
Diversified transporters and pathways for bacteriocin secretion in gram-positive bacteria
|
|---|---|
| Published in |
Applied Microbiology and Biotechnology, March 2018
|
| DOI | 10.1007/s00253-018-8917-5 |
| Pubmed ID | |
| Authors |
Sen Zheng, Kenji Sonomoto |
| Abstract |
Bacteriocins are ribosomally synthesised small antimicrobial peptides produced from a wide range of bacteria, and also rich sources for potential alternatives to traditional antibiotics. Many bacteriocins have highly specific antibacterial activity against target pathogens, even including drug-resistant bacteria such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus. As the final and essential step during biosynthesis, the leader sequence removal and exportation of matured bacteriocin are lacking of research and therefore the last to be understood. In respect of production, bacteriocin precursor peptides are processed and exported by a group of membrane proteins from the ATP-binding cassette transporter family. The main aims of this article are to summarise knowledge till now on the leader signal and correlated transporters for bacteriocin secretion in gram-positive bacteria in a review for the first time, to introduce different strategies for higher production, and to offer new insights into many essential but still unanswered questions above for the purpose of more efficient bacteriocin utilisation. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 66 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 15% |
| Researcher | 10 | 15% |
| Student > Bachelor | 9 | 14% |
| Student > Master | 9 | 14% |
| Professor | 3 | 5% |
| Other | 9 | 14% |
| Unknown | 16 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 23 | 35% |
| Agricultural and Biological Sciences | 10 | 15% |
| Immunology and Microbiology | 4 | 6% |
| Chemistry | 3 | 5% |
| Medicine and Dentistry | 2 | 3% |
| Other | 4 | 6% |
| Unknown | 20 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2018.
All research outputs
#21,608,038
of 24,119,703 outputs
Outputs from Applied Microbiology and Biotechnology
#6,994
of 8,034 outputs
Outputs of similar age
#296,936
of 336,040 outputs
Outputs of similar age from Applied Microbiology and Biotechnology
#125
of 143 outputs
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