| Title |
Polymorphisms of two histamine-metabolizing enzymes genes and childhood allergic asthma: a case control study
|
|---|---|
| Published in |
Clinical and Molecular Allergy, November 2010
|
| DOI | 10.1186/1476-7961-8-14 |
| Pubmed ID | |
| Authors |
Aleksandra Szczepankiewicz, Anna Bręborowicz, Paulina Sobkowiak, Anna Popiel |
| Abstract |
Histamine-metabolizing enzymes (N-methyltransferase and amiloride binding protein 1) are responsible for histamine degradation, a biogenic amine involved in allergic inflammation. Genetic variants of HNMT and ABP1 genes were found to be associated with altered enzyme activity. We hypothesized that alleles leading to decreased enzyme activity and, therefore, decreased inactivation of histamine may be responsible for altered susceptibility to asthma. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 3% |
| Unknown | 30 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 32% |
| Student > Bachelor | 8 | 26% |
| Researcher | 4 | 13% |
| Other | 2 | 6% |
| Student > Ph. D. Student | 2 | 6% |
| Other | 3 | 10% |
| Unknown | 2 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 29% |
| Agricultural and Biological Sciences | 5 | 16% |
| Nursing and Health Professions | 3 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
| Biochemistry, Genetics and Molecular Biology | 2 | 6% |
| Other | 7 | 23% |
| Unknown | 3 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2014.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from Clinical and Molecular Allergy
#118
of 214 outputs
Outputs of similar age
#35,995
of 100,306 outputs
Outputs of similar age from Clinical and Molecular Allergy
#1
of 3 outputs
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So far Altmetric has tracked 214 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
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