| Title |
Molybdate transport and regulation in bacteria
|
|---|---|
| Published in |
Archives of Microbiology, October 1997
|
| DOI | 10.1007/s002030050508 |
| Pubmed ID | |
| Authors |
A. M. Grunden, K. T. Shanmugam |
| Abstract |
Molybdate is transported in bacteria by a high-affinity transport system composed of a periplasmic binding protein, an integral membrane protein, and an energizer protein. These three proteins are coded by modA, modB, and modC genes, respectively. The ModA, ModB, and ModC proteins from various organisms (Escherichia coli, Haemophilus influenzae, Azotobacter vinelandii, and Rhodobacter capsulatus) are very similar. The lowest Km value reported for molybdate in the molybdate transport process is approximately 50 nM. In a mod mutant, molybdate is transported by the sulfate transport system or by a nonspecific anion transporter. Molybdate transport is tightly coupled to utilization in E. coli and Klebsiella pneumoniae, while other dinitrogen-fixing organisms appear to have a molybdenum storage protein. In all organisms studied so far, molybdate transport genes are regulated by a repressor protein, ModE. The ModE-molybdate complex binds to the sequences TAYAT (Y = T or C) in the operator/ promoter region in E. coli and prevents transcription of the modABCD operon. The ModE-molybdate complex binds to DNA as a homodimer in E. coli and possibly in other organisms as well. In R. capsulatus, however, two ModE homologues (MopAB proteins) are required for repression. |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 1% |
| Germany | 1 | 1% |
| Chile | 1 | 1% |
| India | 1 | 1% |
| Argentina | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 85 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 27% |
| Researcher | 19 | 21% |
| Student > Master | 9 | 10% |
| Student > Bachelor | 7 | 8% |
| Other | 4 | 4% |
| Other | 10 | 11% |
| Unknown | 17 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 36% |
| Biochemistry, Genetics and Molecular Biology | 22 | 24% |
| Chemistry | 4 | 4% |
| Environmental Science | 3 | 3% |
| Earth and Planetary Sciences | 3 | 3% |
| Other | 5 | 5% |
| Unknown | 21 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2016.
All research outputs
#3,798,611
of 25,374,647 outputs
Outputs from Archives of Microbiology
#116
of 3,119 outputs
Outputs of similar age
#2,228
of 28,974 outputs
Outputs of similar age from Archives of Microbiology
#2
of 18 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,119 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 28,974 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.