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Chromosomal localization of three human genes coding for A15, L6, and S5.7(TAPA1): all members of the transmembrane 4 superfamily of proteins

Overview of attention for article published in Immunogenetics, March 1994
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Title
Chromosomal localization of three human genes coding for A15, L6, and S5.7(TAPA1): all members of the transmembrane 4 superfamily of proteins
Published in
Immunogenetics, March 1994
DOI 10.1007/bf00189229
Pubmed ID
Authors

Kimmo I. Virtaneva, Nobuhiko Emi, John S. Marken, Alejandro Aruffo, Carol Jones, Nigel K. Spurr, Jim P. Schröder

Abstract

The A15, L6, and S5.7(TAPA1) proteins are members of the transmembrane 4 superfamily (TM4SF). The A15 is expressed in immature human T cells and in the human brain. The MXS1(CCG-B7) gene which codes for A15 contains triplet nucleotide repeats which have been associated with neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome, and myotonic dystrophy. The L6 antigen is mainly expressed in lung, breast, colon, ovarian carcinomas, and healthy epithelial tissue in humans. The S5.7(TAPA1) antigen is expressed in most human cell lines and is shown to be associated with B-cell surface molecules CD19 and Leu-13. In this study we have used interspecies specific somatic cell hybrids and human-specific cDNA probes to localize the A15 (MXS1), L6 (M3S1), and TAPA1 genes to Xq11, 3q21-25, and 11p15.5, respectively.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Professor 2 13%
Student > Ph. D. Student 2 13%
Lecturer 1 7%
Student > Bachelor 1 7%
Other 3 20%
Unknown 3 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 40%
Biochemistry, Genetics and Molecular Biology 2 13%
Medicine and Dentistry 2 13%
Immunology and Microbiology 1 7%
Neuroscience 1 7%
Other 0 0%
Unknown 3 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2024.
All research outputs
#7,454,066
of 22,788,370 outputs
Outputs from Immunogenetics
#323
of 1,202 outputs
Outputs of similar age
#6,499
of 22,502 outputs
Outputs of similar age from Immunogenetics
#4
of 10 outputs
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