| Title |
The Effect of Chronic Exercise Training on Leptin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
|
|---|---|
| Published in |
Sports Medicine, March 2018
|
| DOI | 10.1007/s40279-018-0897-1 |
| Pubmed ID | |
| Authors |
Michael V. Fedewa, Elizabeth D. Hathaway, Christie L. Ward-Ritacco, Tyler D. Williams, Ward C. Dobbs |
| Abstract |
Leptin is a hormone associated with satiety, lipid oxidation, energy expenditure, and energy homeostasis. To date, the current body of research examining the effect of chronic exercise training on leptin has yielded inconsistent results. The purpose of this meta-analysis was to provide a quantitative estimate of the magnitude of change in leptin levels following participation in exercise interventions lasting ≥ 2 weeks. All studies included were peer-reviewed and published in English. To be included, studies randomized human participants to an exercise training group or non-exercise comparison group for an exercise training intervention. Leptin levels were measured at baseline, during, and/or after completion of the exercise training program. Random-effects models were used to aggregate a mean effect size (ES) and 95% confidence intervals (CIs), and identify potential moderators. Seventy-two randomized controlled trials met the inclusion criteria and resulted in 107 effects (n = 3826). The mean ES of 0.24 (95% CI 0.16-0.32, p < 0.0001) indicated a decrease in leptin following an exercise training program. A decrease in %Fat (β = - 0.07, p < 0.01) was associated with a decrease in leptin after accounting for the type of control group (β = - 0.38, p < 0.0001) used in each study. These results suggest that engaging in chronic exercise training (≥ 2 weeks) is associated with a decrease in leptin levels for individuals regardless of age and sex. However, a greater decrease in leptin occurred with a decreased percentage of body fat. |
X Demographics
The data shown below were collected from the profiles of 29 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 10 | 34% |
| Spain | 2 | 7% |
| Sweden | 1 | 3% |
| Chile | 1 | 3% |
| New Zealand | 1 | 3% |
| United Kingdom | 1 | 3% |
| Canada | 1 | 3% |
| Ireland | 1 | 3% |
| Slovenia | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 9 | 31% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 16 | 55% |
| Scientists | 8 | 28% |
| Practitioners (doctors, other healthcare professionals) | 4 | 14% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 141 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 23 | 16% |
| Student > Ph. D. Student | 15 | 11% |
| Student > Doctoral Student | 12 | 9% |
| Student > Bachelor | 12 | 9% |
| Student > Postgraduate | 7 | 5% |
| Other | 24 | 17% |
| Unknown | 48 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 24 | 17% |
| Medicine and Dentistry | 19 | 13% |
| Nursing and Health Professions | 10 | 7% |
| Biochemistry, Genetics and Molecular Biology | 9 | 6% |
| Neuroscience | 6 | 4% |
| Other | 14 | 10% |
| Unknown | 59 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2022.
All research outputs
#1,074,381
of 24,719,968 outputs
Outputs from Sports Medicine
#937
of 2,863 outputs
Outputs of similar age
#24,315
of 335,167 outputs
Outputs of similar age from Sports Medicine
#24
of 60 outputs
Altmetric has tracked 24,719,968 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,863 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 54.8. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,167 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.