| Title |
Genetic contribution to vestibular diseases
|
|---|---|
| Published in |
Journal of Neurology, March 2018
|
| DOI | 10.1007/s00415-018-8842-7 |
| Pubmed ID | |
| Authors |
Alvaro Gallego-Martinez, Juan Manuel Espinosa-Sanchez, Jose Antonio Lopez-Escamez |
| Abstract |
Growing evidence supports the contribution of allelic variation to vestibular disorders. Heritability attributed to rare allelic variants is found in familial vestibular syndromes such as enlarged vestibular aqueduct syndrome or familial Meniere disease. However, the involvement of common allelic variants as key regulators of physiological processes in common and rare vestibular diseases is starting to be deciphered, including motion sickness or sporadic Meniere disease. The genetic contribution to most of the vestibular disorders is still largely unknown. This review will outline the role of common and rare variants in human genome to episodic vestibular syndromes, progressive vestibular syndrome, and hereditary sensorineural hearing loss associated with vestibular phenotype. Future genomic studies and network analyses of omic data will clarify the pathway towards a personalized stratification of treatments. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | 29% |
| Venezuela, Bolivarian Republic of | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Scientists | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 13% |
| Student > Ph. D. Student | 5 | 9% |
| Student > Doctoral Student | 5 | 9% |
| Student > Master | 4 | 7% |
| Student > Bachelor | 4 | 7% |
| Other | 13 | 24% |
| Unknown | 17 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 18 | 33% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Neuroscience | 4 | 7% |
| Unspecified | 3 | 5% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 19 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2021.
All research outputs
#4,182,350
of 23,028,364 outputs
Outputs from Journal of Neurology
#1,001
of 4,524 outputs
Outputs of similar age
#83,161
of 330,380 outputs
Outputs of similar age from Journal of Neurology
#21
of 76 outputs
Altmetric has tracked 23,028,364 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,524 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done well, scoring higher than 77% of its peers.
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We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.