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Higher order arrangement of the eukaryotic nuclear bodies

Overview of attention for article published in Proceedings of the National Academy of Sciences of the United States of America, October 2002
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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1 patent
wikipedia
2 Wikipedia pages

Citations

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167 Dimensions

Readers on

mendeley
109 Mendeley
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Title
Higher order arrangement of the eukaryotic nuclear bodies
Published in
Proceedings of the National Academy of Sciences of the United States of America, October 2002
DOI 10.1073/pnas.212483099
Pubmed ID
Authors

I-Fan Wang, Narsa M. Reddy, C.-K. James Shen

Abstract

The nuclei of eukaryotic cells consist of discrete substructures. These substructures include the nuclear bodies, which have been implicated in a number of biological processes such as transcription and splicing. However, for most nuclear bodies, the details of involvement in these processes in relation to their three-dimensional distributions in the nucleus are still unclear. Through the analysis of TDP, a protein functional in both transcriptional repression and alternative splicing, we have identified a new category of nuclear bodies within which the TDP molecules reside. Remarkably, the TDP bodies (TBs) colocalize or overlap with several different types of nuclear bodies previously suggested to function in transcription or splicing. Of these nuclear bodies, the Gemini of coiled bodies (GEM) seems to associate with TB through the interaction between survival motor neuron (SMN) protein and TDP. Furthermore, TB sometimes appears to be the bridge of two or more of these other nuclear bodies. Our data suggest the existence of a hierarchy and possibly functional arrangement of the nuclear bodies within the eukaryotic nuclei.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
United States 1 <1%
Portugal 1 <1%
Czechia 1 <1%
Unknown 104 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 32 29%
Student > Ph. D. Student 22 20%
Professor > Associate Professor 7 6%
Student > Master 7 6%
Student > Bachelor 6 6%
Other 19 17%
Unknown 16 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 40 37%
Biochemistry, Genetics and Molecular Biology 29 27%
Neuroscience 11 10%
Medicine and Dentistry 9 8%
Physics and Astronomy 3 3%
Other 0 0%
Unknown 17 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2018.
All research outputs
#5,225,908
of 24,625,114 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#46,893
of 101,438 outputs
Outputs of similar age
#8,379
of 48,214 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#190
of 484 outputs
Altmetric has tracked 24,625,114 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 101,438 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.8. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 48,214 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 484 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.